摘要
目的:观察补脾益肺法配合针刺疗法对重度颅脑损伤引发肺部感染的干预作用。方法:76例重度颅脑损伤引发肺部感染者随机平均分为对照组和观察组。对照组给予常规疗法,观察组在对照组治疗基础上给予补脾益肺中药配合针刺疗法。比较两组患者临床疗效、肺部感染抗生素使用时间、血清白蛋白(serum albumin,ALB)水平及胃肠道不良反应发生情况。结果:观察组痊愈24例,痊愈率63.16%,明显高于对照组痊愈率(36.84%);观察组有效37例,有效率97.37%,明显高于对照组(71.05%),差异有统计学意义(P<0.05)。观察组肺部感染使用抗生素时间[(2.19±0.72)d]显著短于对照组[(4.76±1.03)d](P<0.05)。治疗前对照组ALB水平[(38.04±3.31)g·L^(-1)]显著高于治疗后[(36.29±2.74)g·L^(-1)],差异有统计学意义(P<0.05);观察组治疗后ALB水平[(33.14±1.35)g·L^(-1)]与对照组ALB水平[(36.29±2.74)g·L^(-1)]比较,差异有统计学意义(P<0.05)。观察组轻度胃肠道不良反应1例;对照组重度胃肠道不良反应2例,轻度胃肠道不良反应5例;观察组胃肠道不良反应发生率为2.63%,明显低于对照组的18.42%,差异具有统计学意义(P<0.05)。结论:补脾益肺中药配合针刺疗法可提高重度颅脑损伤引发的肺部感染疗效,减少胃肠道不良反应,缩短抗生素使用时间。
Objective：To observe the intervention effect of Bupi Yifei Method combined with acupuncture on pulmonary infection caused by severe craniocerebral injury.Methods：76 patients with severe brain injury caused by pulmonary infection were randomly divided into control group and observation group.The control group was given conventional therapy and the observation group was given the traditional Chinese medicine of Bupi Yifei combined with acupuncture in addition to that of the control group.The clinical efficacy,antibiotic use time of lung infection,serum albumin（ALB）level and gastrointestinal adverse reactions between the two groups were compared.Results：In the observation group,24 cases were cured and the cure rate was 63.16%,which was significantly higher than that（36.84%）of the control group（P〈0.05）.There were 37 cases in the observation group that was effectively cured and the effective rate was 97.37%,which was significantly higher than that（71.05%）of the control group（P〈0.05）.The average time of antibiotic use（2.19 d）in the observation group was significantly shorter than that in the control group（4.76 d）（P〈0.05）.The ALB level of the control group before treatment was（38.04±3.31 g·L^-1）,which was significantly higher than that（33.14±1.35 g·L^-1）after treatment（P〈0.05）;the ALB level in the observation group was（36.29±2.74g·L^-1）after treatment,which was significantly higher than that（33.14±1.35 g·L^-1）of the control group（P〈0.05）.There was1 case of mild gastrointestinal side effects in the observation group and 2 cases of severe gastrointestinal side effects in the control group as well as 5 cases of mild gastrointestinal side effects.The incidence of gastrointestinal adverse reactions in the observation group was 2.63%,which was significantly lower than that（18.42%）of the control group（P〈0.05）.Conclusion：Bupi Yifei method combined with acupuncture can improve the efficacy of pulmonary infection caused by severe craniocer
作者
李南
孙超龙
杜彩霞
赵献敏
张松江
朱艳琴
王权
LI Nan;SUN Chaolong;DU Caixia;ZHAO Xianmin;ZHANG Songjiang;ZHU Yanqin;WANG Quan(The Staff Worker Hospital of Henan Province,Zhengzhou Henan China 450000;The Affiliated Hospital to Chinese Medicine Research Institute of Henan Province,Zhengzhou Henan China 450004;Henan University of Chinese Medicine,Zhengzhou Henan China 450046)
出处
《中医学报》
CAS
2018年第10期1870-1873,共4页
Acta Chinese Medicine
基金
国家自然科学基金资助项目(81373852)
河南省重点科技攻关项目(152102310100)
河南省高等学校重点科研项目(15A310018)
河南省中医药科学研究专项课题项目(2014ZY02044)
关键词
补脾益肺法
针刺疗法
肺部感染
颅脑损伤
血清白蛋白
中西医结合
Bupi Yifei method
acupuncture
pulmonary infection
craniocerebral injury
serum albumin
Integrative medicine
