摘要
目的观察孟鲁司特联合布地奈德治疗小儿咳嗽变异性哮喘（CVA）的临床效果。方法选择沈阳市儿童医院2016—2018年收冶的CVA患儿97例，随机分为观察组49例和对照组48例。对照组应用布地奈德雾化吸人，观察组在对照组基础上加用孟鲁司特钠咀嚼片，比较两组患儿肺功能和炎性因子变化。结果两组患儿治疗前肺功能和炎性因子各指标差异无统计学意义（P〉0.05）；治疗后上述指标差异均有统计学意义（P〈0．05）。结论孟鲁司特联合布地奈德治疗小儿CVA床效果显著，能够有效改善患儿的呼吸功能和炎症水平，值得临床推广应用。
Objective To observe the clinical effects of montelukast combined with budesonide on cough varriant asthma （CVA） in children. Methods A total of 97 children with CVA from 2016 to 2018 were collected in our hospital and divided into observation group （49 cases） and control group （48 cases） randomly. The control group accepted budesonide by atomization inhalation, while the observation group accepted montelukast based on that. We compared the pulmonary function and inflammatory factors between two groups. Results There were no significant differences in pulmonary function and inflammatory factors between two groups before treatment （P〉0.05）, while there were significant differences after treatment （P〈0.05）. Conclusion The application of montelukast combined with budesonide on CVA in children are effective, and could improve the pulmonary function and inflammatory level, which should be promoted in clinical application.
作者
郝亮亮
HAO Liangliang(No. 5 Department of Internal Medicine, Shenyang Children＇s Hospital, Shenyang 110032, Liaoning Province, China)
出处
《中国实用乡村医生杂志》
2018年第10期62-64,共3页
Chinese Practical Journal of Rural Doctor
