摘要
结直肠癌前病变主要包括结直肠腺瘤与炎症性肠病。对结直肠癌前病变的中医理论进行探讨分析,提出其病因为饮食不节、情志失调、外邪侵袭、禀赋不足;基本病机为脾虚不健,湿浊瘀毒阻滞肠道;主要病理因素为癌毒、湿浊、瘀血;治疗以扶正祛邪为原则,以益气健脾为要,解毒化湿祛瘀并举。结直肠癌前病变的类型不同则病理因素与治疗亦各有偏重。腺瘤多以癌毒兼夹瘀血为主,尤重祛瘀散积;炎症性肠病多以癌毒兼夹湿浊为主,尤重化湿泄浊。
Colorectal precancerous lesions mainly include colorectal adenoma and inflammatory bowel disease.The traditional Chinese medicine（ TCM） theory of colorectal precancerous lesions was discussed in this paper,and it pointed out that pathogenesis was improper diet,emotional frustration,external evil invasion and inadequate natural endowment,and the basic etiology was spleen qi deficiency,dampness and turbidity stasis toxin blocking the intestinal tract. The main pathological factors were cancer toxin,damp turbidity,and blood stasis,and basic therapeutic principle was strengthening the body resistance to eliminate pathogenic factors,taking the therapy of tonifying qi and invigorating spleen as core and dissipating dampness,removing blood stasis and removing toxicity as integrated treatment. The pathological factors and treatment were different in different types of colorectal precancerous lesions,so the pathological factors and treatment were different. Specifically,the main pathological factor of colorectal adenoma was cancer toxin,accompanied with blood stasis,which was primarily treated with removing blood stasis and eliminating stagnation. The main pathological factor of inflammatory bowel disease was cancer toxin,accompanied with damp turbidity,which was primarily treated with dissipating dampness and dispelling turbidity.
作者
王俊壹
程海波
周仲瑛
WANG Junyi;CHENG Haibo;ZHOU Zhongying(Jiangsu Provincial Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor,Nanjing Uni-versity of Chinese Medicine,Nanjing,210023)
出处
《中医杂志》
CSCD
北大核心
2018年第21期1819-1823,共5页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81573910)
科技部重点研发计划(2017YFC1700602)
江苏高校优势学科建设工程资助项目(PAPD)
关键词
结直肠癌
癌前病变
直肠腺癌
炎症性肠病
colorectal cancer
precancerous lesions
colorectal adenoma
inflammatory bowel disease
