摘要
目的研究腹腔镜结肠癌根治术治疗结直肠癌的安全性及对血清miR-29a、MMP-7水平的改善作用。方法选取我院收治的行结肠癌根治术的患者98例,根据手术方式的不同分为研究组(n=56)与对照组(n=42)。对照组采取常规开腹手术,而研究组患者采取腹腔镜手术治疗。比较两种术式对患者的并发症及血清miR-29a、MMP-7水平改善情况。结果研究组患者的并发症总发生率显著低于对照组(P<0.05)。术后7 d,两组患者的血清miR-29a、MMP-7水平均降低,且研究组低于对照组(P<0.05)。结论腹腔镜下行结直肠癌根治术安全性较高,且能明显改善患者血清miR-29a、MMP-7水平,具有良好的临床应用价值。
Objective To study the safety of laparoscopic radical resection for colorectal cancer and its effect on improvement of serum levels of miR-29a and MMP-7. Methods Ninety-eight patients with colon cancer underwent radical resection were divided into study group （n=56） and control group （n=42） according to different surgical methods. The control group received routine laparotomy, while the study group underwent laparoscopic surgery. The complicatons and the improvement of serum miR-29a and MMP-7 levels were compared between the two groups. Results The total incidence of complications in the study group was significantly lower than that in the control group （P〈0.05）. At 7 days after operation, the levels of serum miR-29a and MMP-7 in both groups decreased, and those of the study group were lower than the control group （P〈0.05）. Conclusion Laparoscopic radical resection for colorectal cancer is of high safety and can improve the levels of serum miR-29a and MMP-7, which has a good clinical value.
作者
马永逸
张引涛
MA Yong-yi;ZHANG Yin-tao(the First People＇s Hospital of Xianyang City,Xianyang 712000,China)
出处
《临床医学研究与实践》
2018年第31期64-65,共2页
Clinical Research and Practice
关键词
腹腔镜
开腹手术
结直肠癌
laparoscopy
laparotomy
colorectal cancer
