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不同剂量羟考酮在宫腔镜术麻醉效果及对寒战、宫缩痛的预防效果

Different doses of oxycodone in anesthetic effect of hysteroscopic surgery and preventive effect of chills and uterine contraction pain
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摘要 目的:探讨不同剂量羟考酮在宫腔镜术麻醉效果及对寒战、宫缩痛的预防效果。方法:将145例宫腔镜手术患者分为A组(71例)及B组(74例),A组静脉注射丙泊酚3 min前静脉注射羟考酮0. 1 mg/kg,B组静脉注射羟考酮0. 15 mg/kg,再使用微量泵泵注丙泊酚维持麻醉,观察麻醉效果及不良反应,对比两组T0-T3时的MAP、SpO_2及HR。结果:A组苏醒时间低于B组(P <0. 05),丙泊酚用量高于B组(P <0. 05); T1、T2时,B组SpO_2及HR低于A组(P <0. 05),A组的呼吸抑制、恶心呕吐发生率低于B组(P <0. 05)。结论:0. 1 mg/kg羟考酮使血流动力学更为平稳,可满足宫腔镜术中、术后的镇痛需求。 Objective: To explore different doses of oxycodone in anesthetic effect of hysteroscopic surgery and preventive effect of chills and uterine contraction pain. Methods: 145 cases of hysteroscopic surgery were selected and divided into Group A (71 cases) and Group B (74 cases). The patients in Group A were treated with intravenous 0.1 mg/kg oxycodone before intravenous propofol for 3 min. The patients in Group B were treated with intravenous 0.15mg /kg oxycodone and then pumped propofol to maintain anesthesia by micropump. The anesthetic effects and adverse reactions were observed, and the MAP, SpO 2 and HR in the two groups were compared from T0 to T3. Results: The waking time of Group A was shorter than that of Group B; the propofol consumption in Group A was higher than that in group B ( P 〈0.05); at T1 and T2, SpO 2 and HR in Group B were lower than those in Group A ( P 〈0.05). The incidence of respiratory depression and nausea and vomiting in Group A was lower than that in Group B ( P 〈0.05). Conclusion: 0.1 mg/kg oxycodone makes hemodynamics more stable, and can meet the demand for analgesia during and after hysteroscopy.
作者 魏育洁 WEI Yujie(Zhengzhou Central Hospital,Henan,Zhengzhou 450000,China)
机构地区 郑州市中心医院
出处 《包头医学院学报》 CAS 2018年第10期74-75,共2页 Journal of Baotou Medical College
关键词 剂量 羟考酮 宫腔镜术 效果 Doses Oxycodone Hysteroscopic surgery Effect
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