摘要
目的观察营养支持在慢性阻塞性肺疾病(COPD)中的治疗疗效。方法 86例COPD患者,遵循随机数字表法分为观察组和对照组,每组43例。对照组采用肠外营养支持治疗,观察组采用肠内营养联合肠外营养支持治疗。比较两组治疗前后的营养指标、免疫指标以及住院时间。结果治疗前,两组患者白蛋白、总蛋白、氧合指数、体重比较差异无统计学意义(P>0.05);治疗后,观察组白蛋白、总蛋白、氧合指数、体重均显著高于对照组,差异具有统计学意义(P<0.05)。治疗前,两组患者免疫球蛋白(Ig)G、IgA、IgM、外周血总淋巴细胞计数(TLC)比较差异无统计学意义(P>0.05);治疗后,观察组IgG、IgA、IgM、TLC均高于对照组,差异具有统计学意义(P<0.05)。观察组患者住院时间为(15.06±3.28)d,对照组患者住院时间为(21.77±4.21)d,观察组患者住院时间显著短于对照组,差异具有统计学意义(t=8.2446, P=0.0000<0.05)。结论营养支持可有效改善COPD患者的营养状况,提高其免疫功能,缩短治疗时间,值得借鉴。
Objective To observe the therapeutic effect of nutritional support in the treatment of chronic obstructive pulmonary disease. Methods A total of 86 COPD patients were divided into observation group and control group according to the random number table method, 43 cases in each group. The control group was treated with parenteral nutrition support, the observation group was given enteral nutrition combined with parenteral nutrition support. The nutritional indexes and immune indexes before and after treatment, length of stay between the two groups were compared. Results Before treatment, there were no significant differences in the albumin, total protein, oxygenation index and body weight between the two groups（P0.05）. After treatment, the levels of albumin, total protein, oxygenation index and body weight in the observation group were significantly higher than those in the control group, the differences were statistically significant（P0.05）. Before treatment, there were no significant differences in the immunoglobulin（Ig） G, IgA, IgM and peripheral blood total lymphocyte count（TLC） between the two groups（P0.05）. After treatment, the levels of IgG, IgA, IgM and TLC in the observation group were significantly higher than those in the control group, the differences were statistically significant（P0.05）. The length of stay in the observation group was（15.06±3.28） d, that in the control group was（21.77±4.21） d, the length of stay in the observation group was significantly shorter than that in the control group, the difference was statistically significant（t=8.2446, P=0.00000.05）. Conclusion Nutritional support can effectively improve the nutritional status of COPD patients, improve their immune function and shorten the treatment time, it is worth learning.
作者
林海容
黄艳媚
邓璀
陈小可
姚桂锐
喻海琼
刘慧
刘念
LIN Hal-tong;HUANG Yan-mei;DENG Cui(The Eighth Affiliated Hospital of Sun Yat-sen University,Shenzhen 518033,China)
出处
《中国实用医药》
2018年第28期6-8,共3页
China Practical Medicine
关键词
营养支持
慢性阻塞性肺疾病
治疗疗效
Nutritional support
Chronic obstructive pulmonary disease
Therapeutic effect
