摘要
目的探讨联合检测血降钙素原、D-二聚体对儿童社区获得性肺炎严重程度及预后的预测价值,为判断儿童社区获得性肺炎的严重程度及预后提供参考。方法选择2015年1月-2017年1月在医院住院的62例儿童社区获得性肺炎患儿分为轻症肺炎组46例和重症肺炎组16例,另选择体检健康儿童29例为健康对照组,比较3组儿童血降钙素原和D-二聚体的水平变化以及患儿死亡组和治愈组此二项指标的差异。结果健康对照组、轻症肺炎组和重症肺炎组年龄、体质量及性别差异均无统计学意义(P>0.05);肺炎组中血降钙素原和D-二聚体较健康对照组均明显升高,差异有统计学意义(P<0.05);同时,重症肺炎组患儿的此2项指标也明显高于轻症肺炎组,差异有统计学意义(P<0.05)。联合检测血降钙素原和D-二聚体对儿童社区获得性肺炎诊断价值明显高于单独检测血降钙素原,死亡组血降钙素原、D-二聚体指标显著高于治愈组,差异均有统计学意义(P<0.05)。结论血降钙素原和D-二聚体检测对于儿童社区获得性肺炎严重程度及预后具有一定的作用。
Objective To explore the value of joint detection of serum procalcitonin and D-dimer in evaluation of severity and prognosis of children with community-acquired pneumonia,provide reference for judging severity and prognosis of community-acquired pneumonia in children. Methods From January 2015 to January 2017,62 hospitalized children with community-acquired pneumonia were selected and divided into mild pneumonia group（ 46 children） and severe pneumonia group（ 16 children）,and 29 healthy children receiving physical examination during the same period were selected as healthy control group. The levels of serum procalcitonin and D-dimer in the three groups were compared. The levels of serum procalcitonin and D-dimer were also compared between death group and cure group. Results There was no statistically significant difference in age,weight,and gender among healthy control group,mild pneumonia group,and severe pneumonia group（ P〉0. 05）. The levels of serum procalcitonin and D-dimer in pneumonia group were statistically significantly higher than those in healthy control group（ P〈0. 05）. The levels of serum procalcitonin and D-dimer in severe pneumonia group were statistically significantly higher than those in mild pneumonia group（ P〈0. 05）. The diagnostic value of joint detection of serum procalcitonin and D-dimer for pediatric community-acquired pneumonia was statistically significantly higher than that of single detection of serum procalcitonin; the levels of serum procalcitonin and D-dimer in death groyp were statistically significantly higher than those in cure group（ P〈 0. 05）.Conclusion Joint detection of serum procalcitonin and D-dimer plays an important role in evaluating the severity and prognosis of pediatric community-acquired pneumonia.
作者
曾德润
杨敏
ZENG De-Run;YANG Min(General Hospital of Panzhihua Iron and Steel Company Group,Panzhihua,Sichuan 617000,China)
出处
《中国妇幼保健》
CAS
2018年第19期4421-4423,共3页
Maternal and Child Health Care of China
关键词
儿童社区获得性肺炎
血降钙素原
D-二聚体
严重程度
预后
Pediatric community-acquired pneumonia
Serum procalcitonin
D-dimer
Degree of severity
Prognosis
