摘要
目的观察肺肾双补膏联合三伏贴治疗肺肾两虚型慢性阻塞性肺疾病(COPD)稳定期的临床疗效,及其对患者生活质量、肺功能的影响。方法将120例肺肾两虚型COPD稳定期患者按随机数字表法分为2组。对照组60例予西医常规治疗;治疗组60例在对照组治疗的基础上加用肺肾双补膏联合三伏贴治疗。2组均治疗1年后统计疗效,比较2组治疗前后生活质量及肺功能的变化情况,生活质量采用COPD评估测试量表(CAT)评分进行评定,包括咳嗽、咯痰、胸闷、气喘、做事影响、外出信心、睡眠及精力8个方面内容;肺功能水平评定指标包括第1 s用力呼气容积(FEV_1)、用力肺活量(FVC)、FEV_1/FVC及FEV_1占预计值百分比(FEV1%)。结果治疗组总有效率91.67%,对照组总有效率75.00%,治疗组疗效优于对照组(P<0.05); 2组治疗后CAT各项评分及总分与本组治疗前比较均明显降低(P<0.05),且治疗组治疗后CAT各项评分及总分均低于对照组治疗后水平(P<0.05); 2组治疗后FEV_1、FVC、FEV_1/FVC及FEV_1%与本组治疗前比较均明显增加(P<0.05),且治疗组治疗后FEV_1、FVC、FEV_1/FVC及FEV_1%均高于对照组治疗后(P<0.05)。结论肺肾双补膏联合三伏贴治疗肺肾两虚型COPD稳定期疗效确切,可明显改善患者临床症状,改善生活质量,提高肺功能。
Objective To observe the effect of Feishen Shuangbu ointment combined with dog days plaster on patients with chronic obstructive pulmonary disease （COPD） at stable stage in lung and kidney deficiency syndrome and its effect on quality of life and pulmonary function. Methods 120 patients with stable COPD in Lung and Kidney deficiency syndrome were randomly divided into two groups. 60 patients in control group were treated by conventional western medicine. 60 patients in treatment group were treated by Feishen Shuangbu ointment combined with dog days plaster on the basis of the control group. The efficacy of the two groups were measured after 1 year of treatment. The changes of quality of life and lung function before and after treatment were compared. The quality of life was assessed by the COPD assessment test scale （CAT）, including cough,expectoration,chest tightness,wheezing, work impact, out-of-office confidence, sleep and energy. Pulmonary function level measures included 1st forced expiratory volume （FEV 1）, forced vital capacity （FVC）, FEV 1/FVC, and FEV 1 as a percentage of predicted value （FEV 1 % pred）. Results The total effective rate was 91.67% in the treatment group and 75.00 % in the control group. The treatment group was better than the control group（ P 〈0.05）. The CAT scores and total scores of the two groups were significantly lower than those before treatment （ P 〈0.05）. The scores and total scores of CAT in the treatment group were lower than those in the control group （ P 〈0.05）. The levels of FEV 1, FVC,FEV 1/FVC and FEV 1 % pred in the two groups were significantly increased compared with those in the group before treatment （ P 〈0.05）, and the FEV 1, FVC, FEV 1/FVC and FEV 1 % pred levels after treatment in the treatment group were higher than the control group after treatment （ P 〈0.05）. Conclusion The combination of Feishen Shuangbu ointment combined with dog days plaster in the treatment of stable COPD in lung and kidney deficiency synd
作者
张丽
尹玉松
孙义田
季辉
ZHANG Li;YIN Yusong;SUN Yitian(Department of Lung Disease,Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Hebei 061001)
出处
《河北中医》
2018年第10期1477-1481,共5页
Hebei Journal of Traditional Chinese Medicine
基金
河北省中医药管理局2013年度中医药类科研计划课题(编号:2013137)
关键词
肺疾病
慢性阻塞性
中药疗法
膏剂
穴位贴敷法
Lung disease, chronic obstructive
Chinese medicine therapy
Ointment
Acupoint application
