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探讨紫杉醇联合三维适形放疗治疗局部晚期非小细胞癌的临床效果 被引量:1

To Explore the Clinical Efficacy of Paclitaxel Combined with Three-dimensional Conformal Radiotherapy in the Treatment of Locally Advanced Non-small Cell Carcinoma
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摘要 目的探讨分析紫杉醇联合三维适形放疗在临床治疗局部晚期非小细胞癌的效果。方法选择2015年6月至2016年8月我院肿瘤内科收治的80例局部晚期非小细胞癌患者,随机分为对照组、观察组,分别40例。给予对照组患者实施三维适形放疗,给予观察组行紫杉醇联合三维维适形放疗,比较两组患者治疗后效果以及不良反应发生情况。结果观察组总有效率(92.5%)显著优于对照组(75.0%)(P<0.05);不良反应发生率(5.0%)明显低于对照组(15.0%)(P<0.05)。结论给予局部晚期非小细胞癌患者在临床中行紫杉醇联合三维适形放疗,能够有效降低不良反应发生概率,提高治疗效果,具有较高的安全性,使生存质量更佳,临床实用价值高。 Objective To investigate the effect of paclitaxel combined with three-dimensional conformal radiotherapy in the treatment of locally advanced non-small cell carcinoma. Methods From June 2015 to August 2016, 80 patients with locally advanced non-small cell carcinoma were treated in our department of oncology. Randomly divided into the control group and the observation group, 40 cases respectively. The patients in the control group were given three-dimensional conformal radiotherapy, The observation group was treated with paclitaxel combined with three dimensional conformal radiotherapy. The efficacy and adverse reactions of the two groups were compared. Results The total effective rate of the observation group (92.5%) was significantly better than that of the control group (75.0%) (P〈0.05). The incidence of adverse reactions (5.0%) was significantly lower than that of the control group (15.0%) (P〈0.05). Conclusion Paclitaxel combined with three-dimensional conformal radiotherapy in patients with locally advanced non-small cell carcinoma can effectively reduce the incidence of adverse reactions and improve the treatment effect. It has higher safety, better quality of life, and high clinical value.
作者 毛俊年 陈哲 张春荣 MAO Jun-nian;CHEN Zhe;ZHANG Chun-rong(Xinjiang Second Division Korla Hospital,Korla,Xinjiang,841000)
出处 《智慧健康》 2018年第17期126-127,共2页 Smart Healthcare
关键词 局部晚期非小细胞癌 三维适形放疗 紫杉醇 Locally advanced non-small cell carcinoma Three-dimensional conformal radiotherapy Paclitaxel
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