摘要
目的研究阿托伐他汀钙对冠心病患者颈动脉粥样硬化斑块的影响。方法抽取在我院就诊的冠心病颈动脉粥样硬化斑块患者367例进行研究分析,采用随机原则分为观察组与对照组,其中观察组183例,对照组184例;分别给予两组患者不同治疗方式,对照组患者均维持原冠心病常规治疗方式,并在其基础上,给予观察组患者阿托伐他汀钙(20mg/d),执行为期4年的随访调查,观察两组患者临床治疗差异,分析阿托伐他汀钙针对冠心病合并颈动脉粥样硬化斑块的影响。结果观察组综合有效率显著高于对照组,治疗后TC、TG、LDL-C、HDL-C、HCY水平均显著优于对照组,P<0.05,有统计学意义。结论阿托伐他汀钙应用于冠心病患者颈动脉粥样硬化斑块的治疗中效果显著,能够有效抑制动脉粥样硬化趋势,疏通血流循环,降低相关并发症风险,值得推广。
Objective To study the effect of atorvastatin calcium on carotid atherosclerotic plaque in patients with coronary heart disease. Methods Extraction of coronary heart disease in our hospital carotid atherosclerotic plaque in patients with 367 cases of research and analysis, They were random Ly divided into observation group and control group, including 183 cases in observation group and 184 cases in control group, using random sampling principle, they were divided into observation groups by computer sampling. In the control group, different treatments were given to the two groups, and the control group maintained the conventional treatment of the original coronary heart disease, and on the basis of this, the patients in the observation group were given atorvastatin calcium（20 mg/d）. A 4-year follow-up survey was performed to observe the difference in clinical treatment between the two groups, and to analyze the effect of atorvastatin calcium on coronary heart disease with carotid atherosclerotic plaque. Results The comprehensive effective rate of the observation group was significantly higher than that of the control group. The levels of TC, TG, LDL-C, HDL-C, HCY and IMT and plaque score were significantly better than those of the control group, P〈 0.05, with statistical significance. Conclusion Atorvastatin calcium is effective in the treatment of carotid atherosclerotic plaque in patients with coronary heart disease. It can effectively inhibit the trend of atherosclerosis, clear blood circulation and reduce the risk of related complications. It is worth promoting.
作者
周吉利
桂红丹
ZHOU Ji-li;GUI Dan-hong(The People＇s Hospital of Lin＇gao County,Sanya,Hainan,571800)
出处
《智慧健康》
2018年第22期31-33,共3页
Smart Healthcare
关键词
阿托伐他汀钙
冠心病
动脉粥样硬化斑块
Atorvastatin calcium
Coronary heart disease
Atherosclerotic plaque
