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特发性不育男性患者精子顶体酶活性分析

Analysis of sperm acrosome enzyme activity in male patients with idiopathic infertility
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摘要 目的分析特发性不育男性患者精子顶体酶活性。方法测定特发性不育男性患者(A组,84例)、因女方输卵管阻塞行卵胞浆内单精子注射的男性患者(B组,41例)和同期健康男性(C组,52例)的精液常规及精子顶体酶活性。结果三组前向运动精子百分比、正常精子形态率和精子浓度均无统计学差异(P>0.05)。A组和B组精子顶体酶活性低于C组[(30.21±9.45)IU/10~6和(19.26±3.02)IU/10~6 vs.(70.61±26.97)IU/106](P<0.05)。结论特发性不育男性患者精子顶体酶活性低下。 Objective To analyze the sperm acrosome enzyme activity in male patients with idiopathic infertility.Methods The semen analysis and acrosome enzyme activity were detected in 84 male patients with idiopathic infertility(group A),41 male patients treated with intracytoplasmic sperm injection(group B)and 52 healthy males(group C).Results The percentage of forward motile sperm,rate of normal sperm morphology and sperm concentration were not different among three groups(P〉0.05).The sperm acrosome enzyme activity was lower in groups of A and B than that in group C [(30.21±9.45)IU/106 and(19.26±3.02)IU/106 vs.(70.61±26.97)IU/106](P〈0.05).Conclusion The sperm acrosome enzyme activity is lower in male patients with idiopathic infertility.
作者 王洪华 俞红英 江世文 林孟远 顾晔 张怡璇 付锦艳 陈道桢 杨亚萍 WANG Honghua;YU Hongying;JIANG Shiwen(Center of Reproductive Medicine,Affiliated Maternity and Child Health Care Hospital of Wuxi,Nanjing Medical University,Wuxi 214002,CHINA)
出处 《江苏医药》 CAS 2018年第9期1017-1018,共2页 Jiangsu Medical Journal
基金 教育部重点实验室开放课题(KLCCB-KF201703)
关键词 特发性不育 精子顶体酶 Idiopathic infertility Sperm acrosome enzyme
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