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1166例结直肠癌临床病理特征分析 被引量:11

Clinicopathologic feature analysis of 1166 cases with colorectal cancer
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摘要 目的探讨吉林省延吉地区结直肠癌发病情况及临床病理特征。方法回顾分析2011年1月至2016年12月延边大学附属医院经手术后病理确诊的1 166例结直肠癌患者的病历资料。结果1 166例结直肠癌病理诊断主要为腺癌和黏液腺癌,男719例(61.7%)、女447例(38.3%),男女比例为1.61比1。>51岁为发病高峰,占88.7%;>70岁占32.9%。其中直肠癌占44.9%。青年患者(≤40岁)结直肠癌发生率比过去增高,与中老年结直肠癌患者相比,右半结肠癌发生率较高。组织学类型主要为中分化腺癌(86.6%)。淋巴结转移与肿瘤浸润深度和分化程度密切相关。结论吉林省延吉地区结直肠癌发病率呈增长趋势,患者就诊时多为中晚期。早发现、早诊断、早治疗可提高结直肠癌患者生存率。 Objective To study the clinicopathological characteristics of colorectal cancer in Yanji City of Jilin Province.Methods Statistical analysis was conducted in the 1 166 cases of colorectal malignancy treated in Yanbian University Hospital from January 2011 to December 2016.Results Most cases were histologically identified as adenocarcinoma and mucinous adenocarcinoma(1 166 cases).The patient cohort consisted of 719 males(61.7%) and 447 females(38.3%),with a male to female ratio of 1.61 ∶ 1.The high-risk age range for colorectal cancer was over 51 years(making up 88.7% of the total patients).The best predilection site of colorectal cancer was still rectum(44.9%).Compared with their seniors,young patients(age≤40) were prone to be affected by colorectal cancer.Histological type was mainly moderately differentiated adenocarcinoma(86.6%).Lymph node metastasis was closely related to the depth of tumor invasion and differentiation.Conclusions Colorectal cancer is increasing in this area,and most of the patients are in the middle and late stage.Colorectal cancer should be early detection,early diagnosis,and early treatment,so as to improve the survival rate of patients.
作者 金雪梅 朴丽花 金仁顺 韩龙哲 JIN Xuemei;PIAO Lihua;JIN Renshun;HAN Longzhe(Department of Pathology,Yanbian University Hospital,Yanji 133000,China;Department of Histology and Embryology,Medical College of Yanbian University,Yanji 133000,China)
出处 《中国肿瘤外科杂志》 CAS 2018年第5期308-311,共4页 Chinese Journal of Surgical Oncology
关键词 结直肠肿瘤 病理学 分化 浸润深度 转移 Coloreetal neoplasms Pathology Differentiation Invasion Metastasis
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