摘要
目的探讨不同腹腔手术方式治疗卵巢子宫内膜异位囊肿对血清抗苗勒管激素(AMH)水平的影响。方法选取2015年1月至2016年12月海口市妇幼保健院收治的160例卵巢子宫内膜异位囊肿患者。按照手术方式的不同将患者的分成腹腔镜囊肿剥除术组与囊肿凝固术组,每组80例。所有患者随访6个月,观察两组患者术后血清AMH、卵泡刺激素(FSH)、卵泡计数水平。术后病灶复发及相关疼痛复发情况。结果术后1、6个月后囊肿剥除组患者AMH、卵泡计数高于凝固术组(P <0. 05),FSH水平低于凝固术组(P <0. 05);两组患者术中出血量及手术时间比较无统计学差异(P> 0. 05);随访6个月囊肿剥除组患者术后病灶复发率和痛经、性交痛、非经期盆腔痛复发率明显低于凝固术组患者(P <0. 01,P <0. 05)。结论与腹腔镜卵巢子宫内膜异位囊肿凝固术比较,腹腔镜囊肿剥除术后能快速恢复AMH正常水平,增加患者卵泡个数,降低术后病灶复发,改善患者临床症状,在术后卵巢储备功能恢复方面更具优势。
Objective To investigate the influence of different laparoscopic surgery on serum anti-Müllerian hormone（AMH） in patients with ovarian endometriotic cyst. Methods A total of 160 patients with ovarian endometriotic cyst who received treatment at Haikou Hospital of the Maternal and Child Health from January 2015 to December 2016 were selected and divided into two groups according to the operation（laparoscopy cystectomy group and laparoscopy coagulation group,80 cases each）. All the patients were followed up for 6 months. The level of serum AMH,follicle-stimulating hormone（FSH）and antral follicle count（AFC） after the treatment was observed in both groups. Recurrence of lesions and postoperative pain were recorded. Results At 1 and 6 months after the surgery,the AMH and AFC were higher and FSH was lower in cystectomy group（all P〈0. 05）. There was no significant difference in intra-operative bleeding and operation time in two groups（P〈0. 05）. After 6 months of follow-up,the recurrence rate of the lesions and the incidence of dysmenorrhea,intercourse pain and non-menstrual pelvic pain in cystectomy group were significantly lower than those in the coagulation group（P〈0. 01,P〈0. 05）. Conclusion Compared with laparoscopy coagulation for ovarian endometriotic cyst,laparoscopy cystectomy could restore the normal level of AMH quickly,increase the AFC,reduce the recurrence of postoperative lesions,improve the clinical symptoms,and have advantages in the recovery of ovarian reserve function after operation.
作者
郭艳艳
王秀妹
王康
GUO Yan-yan , WANG Xiu-mei, WANG Kang(Department of Gynecology and Obstetrics, Haikou Hospital of the Maternal and Child Health, Haikou, Hainan 570102, China)
出处
《中国临床研究》
CAS
2018年第9期1257-1259,共3页
Chinese Journal of Clinical Research
基金
海南省自然科学基金(20158314)
