摘要
[目的]分析浙江省温岭市大肠癌筛查和早诊早治工作开展情况。[方法]根据《大肠癌早诊早治项目技术方案》,采用危险度评估问卷调查和免疫法大便隐血试验（FOBT）检查相结合的方法进行大肠癌初筛,对初筛结果阳性的高危人群采用电子肠镜作进一步检查。[结果]2011年12月1日-2016年6月30日对温岭市296个村进行筛查,完成初筛36 757人,初筛顺应性为46.34%（36757/79314）。初筛阳性2673例,其中1039人接受肠镜检查,肠镜检查顺应性为38.87%（1039/2673）。共检出早期大肠癌14例（乙状结肠癌7例,直肠癌7例）,检出率为1.35%（14/1039）。肠道腺瘤287例,增生性息肉68例,结肠溃疡3例,检出率分别为27.62%（287/1039）、6.54%（68/1039）和0.29%（3/1039）。男性大肠肿瘤的检出率高于女性（P〈0.01）。随着年龄增长,早期大肠癌的检出率明显增加（P〈0.01）。[结论 ]开展大肠癌早诊早治筛查,有利于早期发现大肠癌及癌前病变。
[Purpose] To review the screening program for colorectal cancer in Wenling city Zhejiang province. [Methods] According to the ＂Protocol of Colorectal Cancer Early Diagnosis and Early Treatment Project＂ of Ministry of Health,the primary screening of colorectal cancer with hazard degree assessment questionnaire survey combining immunoassay fecal occult blood test（FOBT） was conducted in Wenling city. Positive high-risk individuals underwent electronic colonoscopy for further examination. [Results] From December 1,2011 to June 30,2016,residents in 296 villages of Wenling city were screened,and 36 757 persons completed primary screening with a compliance rate of 46.34%（36757/79314）;and 2673 subjects were identified as high risk in the primary screening,of whom 1039 cases underwent colonoscopy with a examination rate of 38.87%（1039/2673）. There were 14 early stage colorectal cancer detected with a detection rate of 1.35%（14/1039）,including 7 cases of sigmoid colon cancer,7 cases of rectal cancer. Intestinal adenoma was detected in 287 cases,hyperplastic polyps in 68 cases,and colon ulcer in 3 cases,with detection rate of 27.62%（278/1039）,6.54%（68/1039） and 0.29%（3/1039）,respectively. Detection rate of colorectal neoplasms in males was higher than that in females（P0.01）;and the detection rate of early stage colorectal cancer increased with the age（P0.01）.[Conclusion] The screening protocol applied in this study is feasible and effective in early detection and diagnosis of colorectal cancer and precancerous conditions.
作者
丁燕
冯俊
姚俊
魏志平
吕小锦
徐欣华
应荣彪
DING Yah;FENG Jun;YAO Jun;WEI Zhi-ping;LYU Xiao-jin;XU Xin-hua;YING Rong-biao(Central Hospital of Taizhou City,Taizhou 317000,China;Caneer Hospital of Taizhou City,Taizhou 317502,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2018年第9期652-655,共4页
China Cancer
关键词
大肠癌
早诊早治
筛查
浙江
colorectal cancer
early diagnosis and treatment
screening
Zhejiang
