摘要
主动脉瓣狭窄是一种渐进性疾病,随着年龄的增长其发生率逐渐增加。严重的主动脉瓣狭窄患者出现呼吸困难、心绞痛、晕厥等症状后,平均生存年限为2~3年,且猝死风险极高。由于传统的外科手术创伤较大、风险高,很多患者因高龄、左心室功能差、存在各种严重的合并症,或者恐惧外科手术而放弃外科治疗。经导管主动脉瓣植入术经过十余年的发展,目前该技术已逐渐成熟并在世界范围开展,并且成为不适合外科手术的主动脉瓣狭窄患者的首选治疗方案。现综述近年来经导管主动脉瓣植入术的研究进展。
Aortic stenosis is a progressive disease that increases with age.After experiencing symptoms such as dyspnea,angina pectoris or syncope in patients with severe aortic valve stenosis,their average life expectancy is 2 to 3 years and the risk of sudden death is extremely high.Due to the larger trauma and higher risk of traditional surgery,many patients refuse the operation due the reasons such as venerable age,fear of surgery,poor left ventricular function or other serious complications.Transcatheter aortic valve replacement（TAVR）has been developed over the past decade and is currently maturing gradually and developing worldwide.Furthermore,it has been the first-line therapy for patients with aortic stenosis who are not suitable for surgery.This paper reviews the progress of TAVR in aspect of clinical studies,indication,complication,and current concerns.
作者
贾圣琪
裴汉军
JIA Shengqi,PEI Hanjun(Department of Cardiology, The First Affiliated Hospital of Baotou Medical College, Baotou 014010, Inner Mongolia, China)
出处
《心血管病学进展》
CAS
2018年第5期746-750,共5页
Advances in Cardiovascular Diseases
