摘要
目的比较连续性静脉-静脉血液滤过(CVVH)与血液透析(HD)治疗尿毒症脑病的疗效。方法 60例尿毒症脑病患者随机分为HD治疗组和CVVH治疗组各30例,比较2组治疗前后GCS评分、NIHSS评分、β2-MG、PTH、BUN、Scr变化情况,并评价疗效。结果与同组治疗前相比,2组治疗后GCS评分、NIHSS评分、β2-MG、PTH、BUN、Scr均改善(P<0.05),但治疗后比较,CVVH组较HD组的GCS评分、NIHSS评分、β2-MG、PTH改善明显(P<0.05)。结论 CVVH治疗尿毒症脑病安全有效,值得临床应用。
Objective To investigate the curative effect of continuous veno venous hemofiltration（CVVH） and hemodialysis（HD） on patients with uremic encephalopathy. Methods Sixty patients with uremic encephalopathy were randomly divided into groups CVVH and HD that received treatment of CVVH and HD respectively.In all patients,the curative effect,glasgow coma scale（GCS）,national institutes of health stroke scale（NIHSS）,β2 microspheresprotein （β 2 MG）,parathyroid hormone （PTH）,blood urea （BUN）,serum creatinine （Scr） were observed before and after therapy. Results Before therapy,the two groups have no significantly difference in the GCS,NIHSS,β 2 MG,PTH,BUN and Scr （ P 〉0.05）.After therapy,BUN and Scr had no obvious diference between CVVH and HD groups（ P 〉0.05）,However,GCS,NIHSS,β 2 MG,PTH had obvious difference between two groups（ P 〈0.05）. Conclusion CVVH therapy can remove stably big molecular toxic substances such as β 2 MG and PTH,CVVH therapy is a more effective measure for patients with uremic encephalopathy than HD.
作者
陈惠霞
邱茜茜
范波胜
CHEN Huixia;QIU Xixi;FAN Bosheng(Department of Nephrology,Central Hospital of Jiaozuo Coal Industry Group,Jiaozuo 454000,China)
出处
《中国实用神经疾病杂志》
2018年第17期1950-1955,共6页
Chinese Journal of Practical Nervous Diseases
关键词
血液滤过
肾透析
尿毒症脑病
hemofiltration；renal dialysis；uremic encephalopathy
