摘要
以丙酮酸和二溴海因为原料制备了溴代丙酮酸。优化工艺条件为:反应温度为50℃,催化剂为对甲苯磺酸,溶剂为甲醇,收率为40%。该新工艺具有操作友好、后处理简单等优势。
Brominated pyruvic acid is an important intermediate, which is synthesized using pyruvic acid and dihromohydantoin as the raw materials. The yield of brominated pyruvic acid is of 40% under the optimum conditions including reaction temperature of 50℃, p -toluene sulphonic acid as catalyst, and methanol as solvent. This novel process has advantages of friendly operation and simple post-processing.
作者
黄子涵
邵国光
胡能
HUANG Zi-han;SHAO Guo-guang;HU Neng(NO.21 Middle School of Changsha,Changsha 410000,China;Changsha University of Science and Engineering,College of Chemical and Biological Engineering,Changsha 410114,China)
出处
《精细化工中间体》
CAS
2018年第3期31-32,48,共3页
Fine Chemical Intermediates
关键词
丙酮酸
二溴海因
溴代丙酮酸
pyruvic acid
dibromohydantoin
brominated pyruvic acid
