摘要
目的分析阴性症状为主的精神分裂症应用喹硫平和利培酮进行治疗的效果。方法抽取2010年8月—2017年8月在我院进行诊治的阴性症状为主的精神分裂疾病患者200例作为研究对象。对照组100例予以利培酮治疗,试验组100例予以喹硫平治疗,对比两组患者的临床治疗效果。结果试验组患者的BPRS评分优于对照组,差异具有统计学意义(P<0.05);试验组患者的SANS评分优于对照组,差异具有统计学意义(t=10.21,P<0.05)。结论对阴性症状精神分裂症患者予以喹硫平治疗的临床效果较利培酮相比,具有更加显著的效果,能够有效改善患者的阴性症状且疗效明确。
Objective To analyze the efcacy of quetiapine and risperidone in the treatment of schizophrenia with negative symptoms. Methods 200 schizophrenic patients with negative symptoms were selected from August 2010 to August 2017. 100 patients in the control group were treated with risperidone. 100 patients in the trial group were treated with quetiapine. The clinical efects of the two groups were compared. Results The BPRS score of the experimental group was better than that of the control group, and the diference was statistically signifcant （P 〈 0.05）. The SANS score of the experimental group was better than that of the control group, and the diference was statistically signifcant （t=10.21, P 〈 0.05）. Conclusion The clinical efect of quetiapine therapy for schizophrenic patients with negative symptoms is more efective than risperidone, and it can efectively improve the negative symptoms and be efective.
出处
《中国继续医学教育》
2018年第26期144-145,共2页
China Continuing Medical Education
关键词
喹硫平
利培酮
阴性症状
精神分裂症
治疗效果
精神评定
quetiapine
risperidone
negative symptoms
schizophrenia
therapeutic efect
mental assessment
