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Nod样受体家族含pyrin结构域蛋白3和嘌呤能离子通道型受体7在急性痛风性关节炎发病中的作用研究进展 被引量:6

Advancement of research on roles of Nod-like receptor family pyrin domain-containing protein 3 and purinergic P2X7 receptor in pathogenesis of acute gouty arthritis
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摘要 Nod样受体家族含pyrin结构域蛋白3(Nod-like receptor family pyrin domain-containing protein 3,NLRP3)和嘌呤能离子通道型受体7(purinergic P2X7 receptor,P2X7R)是近年发现的炎症小体,在多种疾病的发病过程中发挥着重要作用。为了探讨急性痛风性关节炎的发病机制,本文对NLRP3及其在急性痛风性关节炎发病中的作用、P2X7R及其在急性痛风性关节炎发病中的作用、NLRP3和P2X7R的关系以及二者在急性痛风性关节炎发病中的协同作用进行了综述。
出处 《中医正骨》 2018年第8期39-41,49,共4页 The Journal of Traditional Chinese Orthopedics and Traumatology
基金 国家自然科学基金项目(81574005) 湖南省卫生计生委课题(20180781) 湖南省长沙市省市科卫联合科研课题项目(2017225) 湖南省湘潭市医学科研项目(2018xtyx-12)
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