摘要
目的了解陕西省艾滋病病毒感染者和艾滋病患者(HIV/AIDS)合并感染乙型肝炎病毒(HBV)情况。方法对陕西省2011年6月—2016年6月确证的1 018例HIV/AIDS病例进行乙肝五项检测(HBs Ag、HBs Ab、HBe Ag、HBe Ab和HBc Ab),对HIV/AIDS病例的HBV感染情况进行描述性分析。结果 1 018例HIV/AIDS病例中,HBs Ag阳性112例,阳性率为11.00%。共发现19种血清模式,HBs Ab单阳最多,446例,占43.81%;五项全阴307例,占30.16%;"大三阳"16例,占1.57%;"小三阳"30例,占2.95%。彝族HIV/AIDS病例HBs Ag阳性率和"大三阳"率分别为18.31%和5.63%,均高于汉族和其他少数民族的10.45%和1.27%(P<0.05)。结论陕西省HIV/AIDS病例合并HBV感染率高于普通人群,彝族高于汉族和其他少数民族。
Objective To investigate the status of HIV/AIDS patients co-infected with HBV and to provide scientific evidence for HBV prevention and control among HIV/AIDS patients in Shaanxi Province. Methods Totally 1 018 blood specimens were collected from HIV infected patients diagnosed by Shaanxi Provincial Center for Disease Control and Prevention from June 2011 to June 2016. The five HBV markers（HBs Ag,HBs Ab,HBe Ag,HBe Ab,HBc Ab） for HIV/AIDS patients were tested,and a descriptive analysis was conducted for the Hepatitis B infection status of HIV/AIDS patients. Results Of 1 018 HIV/AIDS patients,112 patients（11.00%） were HBs Ag positive. A total of 19 kinds of HBV marker＇s phenotype distribution were found.Of which, the inoculated population（HBs Ag-, HBs Ab＋, HBe Ab-, HBe Ab-, HBc Ab-） were 446 cases（43.81%）,followed by the susceptible population（HBs Ag-,HBs Ab-,HBe Ab-,HBe Ab-,HBc Ab-） which were 307 cases（30.16%）.The great three positive（HBs Ag＋, HBs Ab-, HBe Ag＋, HBe Ab-, HBc Ab＋） were 16 cases（1.57%） and the small three positive（HBs Ag＋,HBs Ab-,HBe Ag-,HBe Ab＋,HBc Ab＋） were 30 cases（2.95%）. The rate of HBs Ag positive（18.31%）and great three positive（HBs Ag＋,HBs Ab-,HBe Ag＋,HBe Ab-,HBc Ab＋）（5.63%） in the Yi nationality were higher than that in the Han nationality and others（10.45%,1.27%）（P〈0.05）. Conclusion The rate of HIV/AIDS patients co-infected with HBV in Shaanxi Province was higher than that in the general population,and the rate for the Yi nationality was higher than that in the Han nationality and others.
作者
张超
付钰淋
任强
李华
邹扬帆
张梦妍
常文辉
ZHANG Chao;FU Yu-lin;REN Qiang;LI Hua;ZOU Yang-tan;ZHANG Meng-yan;CHANG Wen-hui(Department of AIDS Prevention and Control,Shaanxi Provincial Center for Disease Control and Prevention,Xi＇an,Shaanxi 710054,China)
出处
《预防医学》
2018年第9期889-892,896,共5页
CHINA PREVENTIVE MEDICINE JOURNAL
基金
陕西省疾病预防控制重大课题(2014A5)
