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胺碘酮治疗心力衰竭合并快速型心律失常患者的疗效观察与护理 被引量:29

Efficacy of amiodarone in the treatment of heart failure combined with rapid arrhythmia and it nursing measures
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摘要 目的探讨胺碘酮对心力衰竭合并快速型心律失常患者的临床疗效以及护理体会。方法选取82例心力衰竭合并快速型心律失常患者作为研究对象,按照随机双盲法随机分为对照组和观察组,各41例。对照组采用临床综合抗心力衰竭治疗和护理措施,观察组在对照组基础上加用胺碘酮治疗和护理,对比2组患者的临床疗效。结果观察组患者治疗后总有效率为95.12%(39/41),显著高于对照组的78.05%(32/41)(P<0.05);观察组患者治疗后的心率、舒张压、收缩压分别为(61.05±8.96)次/min、(76.54±6.02)mm Hg、(123.98±14.15)mm Hg,优于对照组患者的(69.84±10.03)次/min、(73.24±5.51)mm Hg、(113.87±13.57)mm Hg(P<0.05);观察组患者不良反应发生率为7.31%(3/41),对照组为9.75%(4/41),差异无统计学意义(P>0.05)。结论心力衰竭合并快速型心律失常患者在接受临床常规抗心力衰竭治疗的基础上加用胺碘酮治疗,可有效改善心率和血压,疗效显著,且不良反应轻微。 Objective To investigate the clinical efficacy and nursing experience of amiodarone in the treatment of heart failure combined with rapid arrhythmia. Methods A total of 82 patients with heart failure combined with rapid arrhythmia were enrolled in our hospital,and were divided into two groups according to randomized double-blind method. The patients in the control group were treated with clinical comprehensive antiarrhythmic therapy and nursing,while the patients in the observation group were treated with amiodarone on the basis of the control group. The clinical efficacy of two groups were compared. Results The total effective rate was 95. 12%(39/41) in the observation group,which was significantly higher than 78. 05%(32/41) in the control group(P〈0. 05).After treatment, heart rate, diastolic blood pressure, systolic blood pressure were(61. 05 ±8. 96) times/min,(76. 54 ± 6. 02) mm Hg,(123. 98 ± 14. 15) mm Hg,respectively,which were better than(69. 84 ± 10. 03) times/min,(73. 24 ± 5. 51) mm Hg,(113. 87 ± 13. 57) mm Hg,respectively,in the control group(P〈0. 05). The incidence of adverse reactions was 7. 31%(3/41)in the observation group and 9. 75%(4/41) in the control group,but no significant difference between the two groups was found(P〉0. 05). Conclusion Amiodarone therapy based on conventional anti-heart failure treatment is effective in the treatment of heart failure patients with arrhythmia. It can effectively improve the heart rate and blood pressure of the patients,and has better curative effect,and less adverse reactions.
作者 吴运莲 张元萍 李万敏 WU Yunlian;ZHANG Yuanping;LI Wanmin(Second People's Hospital of Yibin City in Sichuan Province,Yibin,Sichuan,64400)
出处 《实用临床医药杂志》 CAS 2018年第16期13-15,19,共4页 Journal of Clinical Medicine in Practice
关键词 心力衰竭 快速性心律失常 胺碘酮 心率 血压 heart failure rapid arrhythmia amiodarone heart rate blood pressure
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