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法舒地尔+乌拉地尔对慢性肺心病患者PAF及血小板功能影响 被引量:1

Effects of fasudil plus urapidil on PAF and platelet function in patients with chronic pulmonary heart disease
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摘要 目的探讨法舒地尔联合乌拉地尔治疗慢性肺源性心脏病的效果以及对血小板活化因子(PAF)及血小板功能影响。方法选取2013年1月和2017年1月医院收治的慢性肺源性心脏病患者61例,按照患者入院顺序交替分为联合组(n=31)和常规组(n=30),常规组给予常规治疗+法舒地尔治疗,联合组在常规组基础上,加用乌拉地尔治疗,比较两组的治疗效果以及治疗前后血小板活化因子及血小板功能的变化。结果治疗后,联合组的总有效率(93.5%)高于常规组(73.3%)(P<0.05);两组治疗前血小板活化因子(CD62P、CD63)、血小板聚集率、TXB2比较无显著差异(P>0.05),治疗后,联合组低于对照组(P<0.05)。结论法舒地尔联合乌拉地尔治疗慢性肺源性心脏病效果显著,可有效改善患者的临床症状,抑制血小板活化,改善血小板功能。
出处 《西南国防医药》 CAS 2018年第8期743-745,共3页 Medical Journal of National Defending Forces in Southwest China
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