摘要
目的观察自拟补中扶正汤对卵巢癌术后患者胃肠功能、免疫功能的影响。方法选取2015年1月至2017年1月在聊城市中医医院接受卵巢癌手术治疗的86例患者为研究对象,依据随机数字法分为对照组和观察组,各43例。对照组给予术后常规治疗,观察组在对照组治疗的基础上给予本院自拟补中扶正汤治疗。治疗7 d后评估两组患者临床疗效,术后胃肠功能指标及住院时间;观察两组治疗前、后胃肠症状程度及免疫功能的变化情况。结果观察组优良率高于对照组[53.49%(23/43)比23.26%(10/43)](P<0.05)。观察组术后肠鸣音改善时间、肛门排气时间、首次排便时间及住院时间均短于对照组[(17.41±4.08)h比(27.49±4.26)h、(42.13±6.17)h比(58.41±6.58)h、(47.29±5.54)h比(67.28±5.96)h、(9.79±1.12)d比(15.87±2.03)d](P<0.01)。治疗后观察组腹痛、腹胀、胃肠反应评分低于对照组[(0.69±0.19)分比(1.39±0.26)分、(0.95±0.17)分比(1.27±0.25)分、(0.81±0.31)分比(1.46±0.37)分](P<0.01)。治疗后观察组Ig A、Ig M、CD+3、CD+4、CD+8、CD+4/CD+8高于对照组(P<0.01)。结论补中扶正汤能有效促进卵巢癌患者术后胃肠功能尽早恢复,提高术后免疫功能。
Objective To observe the effect of strengthening decoction on gastrointestinal function and immune function of patients with ovarian cancer after operation. Methods From Jan. 2015 to Jan. 2017,86 patients who received ovarian cancer surgery in Liaocheng Hospital of Traditional Chinese Medicine were included in the study. According to the random number method,they were divided into a control group and an observation group,43 patients each. The control group was given regular postoperative treatment,while the observation group was given self-designed strengthening decoction on the basis of the control group＇ s regimen. After 7 days of treatment,the clinical efficacy of the two groups was evaluated and postoperative gastrointestinal function indexes and hospitalization time were observed. The changes of gastrointestinal symptoms and immune function before and after treatment were observed. Results The excellent rate of the observation group was higher than that of the control group[53. 49%（ 23/43） vs 23. 26%（ 10/43） ]（ P〈0. 05）. The bowel sound improvement time,anal exhaust time,postoperative defecation time and hospital stay of the observation group were less than those of the control group[（ 17. 41 ± 4. 08） h vs（ 27. 49 ± 4. 26） h,（ 42. 13 ± 6. 17） h vs（ 58. 41 ± 6. 58） h,（ 47. 29 ± 5. 54） h vs（ 67. 28 ± 5. 96） h,（ 9. 79 ± 1. 12） d vs（ 15. 87 ± 2. 03） d]（ P〈0. 01）. The abdominal pain,abdominal distension,gastrointestinal reaction score of the observation group after treatment were lower than those of the control group[0. 69 ± 0. 19）scores vs（ 1. 39 ± 0. 26） scores,（ 0. 95 ± 0. 17） scores vs（ 1. 27 ± 0. 25） scores,（ 0. 81 ± 0. 31） scores vs（ 1. 46 ± 0. 37）scores]（ P〈0. 01）. Ig A,Ig M,CD＋3,CD＋4,CD＋8,CD＋4/CD＋8 in the observation group after treatment were higher than those in the control group（ P〈0. 01）. Conclusion Strenthening decoction can effectively promote the early recovery of gastrointestinal functio
作者
张志恒
刘玲
孙长侠
ZHANG Zhiheng;LIU Ling;SUN Changxia(Department of Oncology,Liaocheng Hospital of Traditional Chinese Medicine,Liaocheng 252000,Chin)
出处
《医学综述》
2018年第15期3117-3121,共5页
Medical Recapitulate
关键词
卵巢癌
胃肠功能
免疫功能
Ovarian cancer
Gastrointestinal function
Immune function
