摘要
目的分析影响前列腺癌患者生存质量的危险因素。方法回顾性分析2012年2月~2015年3月我院泌尿外科收治的112例前列腺癌患者的临床资料。随访2年,采用肿瘤患者生存质量核心量表(EORTC QLQ-C30)和前列腺癌特异性补充量表(EORTC QLQ-PR25)对患者生存质量进行评估,依据评分结果将患者分为生存质量良好组(A组,78例,得分≥75分)和生存质量不良组(B组,34例,得分﹤75分或死亡),分析影响患者生存质量的相关因素。结果经logistics多因素回归分析结果显示,肿瘤分期、前列腺癌Gleason分级评分、盆腔淋巴结转移、文化程度、付费方式是患者生存质量不佳的独立危险因素。结论前列腺癌患者的肿瘤分期、Gleason评分、盆腔淋巴结转移与否、文化程度、付费方式等是影响治疗后的生存质量的危险因素,临床上应予高度重视。
Objective To analyze the risk factors for quality of life of patients with prostate cancer.Methods The clinical data of 112 patients with prostate cancer treated in the department of urology in our hospital from February 2012 to March2015 were retrospectively analyzed.All patients were followed up for two years.Quality of life of patients was evaluated with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire（EORTC QLQ-C30）and the European Organisation for Research and Treatment of Cancer Quality of Life Prostate module（EORTC QLQ-PR25）.According to the scores,the patients were divided into good quality of life group（group A,78 cases,score≥75 points）and poor quality of life group（group B,34 cases,score〈75 points or dead）.The related factors that affect the quality of life were recorded and analyzed.Results Multivariate Logistics regression analysis showed that tumor stage,Gleason grade score of prostate cancer,pelvic lymph node metastasis,education level and payment were the independent risk factors for poor quality of life of patients.Conclusion The tumor stage,Gleason score,pelvic lymph node metastasis,education level and payment mode affect the quality of life of patients with prostate cancer after treatment,which should be paid more attention.
作者
罗敏
朱玲
刘玲
王婷
LUO Min;ZHU Ling;LIU Ling;WANG Ting(Department of Urology,West China Hospital,Sichuan University,Chengdu 610041,China;Health Management Center,Sichuan University,West China Hospital,Chengdu 610041,China.)
出处
《西部医学》
2018年第8期1200-1202,1206,共4页
Medical Journal of West China
基金
四川大学华西医院学科卓越发展1.3.5工程项目(ZY2016104)
