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卵圆孔未闭(PFO)合并反常栓塞行介入封堵治疗的有效性

Effectiveness of interventional occlusion in patients with patent foramen ovale (PFO) complicated with anomalous embolization
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摘要 目的评价介入封堵治疗在卵圆孔未闭(PFO)合并反常栓塞患者中的有效性。方法对我院接受介入封堵治疗的PFO合并反常栓塞患者35例的临床资料进行回顾性分析,统计封堵成功率,对比患者术前和术后3 d经颅超声多普勒声学造影检查(c TCD)结果,术前、术后3、6个月采用头痛影响测定-6量表(HIT-6)进行评分。结果本组患者封堵成功率为91.43%;术后3 d患者c TCD检查结果等级分布明显优于术前(P<0.05),且术后0~I级占比远高于术前(P<0.05);术后3、6个月HIT-6评分均明显低于术前(P<0.05),且术后6个月评分远低于术后3个月(P<0.05)。结论 PFO合并反常栓塞行介入封堵治疗可获得理想的临床效果,能够改善脑部血流,控制偏头痛程度。 Objective To evaluate the effectiveness of interventional occlusion in patients with patent foramen ovale(PFO) complicated with anomalous embolization. Methods The data of 35 PFO patients complicated with anomalous embolization who received interventional occlusion in our hospital were retrospectively analyzed. The success rate of occlusion was counted. The results of transcranial Doppler ultrasound examination(c TCD) were compared between preoperative and postoperative 3 d. The impact of headaches on the 6 scale(HIT-6) scores preoperative, postoperative 3 months and6 months were evaluated. Results The success rate of occlusion in 35 patients was 91.43%. The results of c TCD examination ranked distribution at postoperative 3 d were significantly better than those preoperative(P〈0.05), and the composition ratio of 0-I was much higher than that preoperative(P〈0.05). The scores of HIT-6 at 3 months and 6 months postoperative were much lower than those preoperative(P〈0.05), and the score at 6 months postoperative was much lower than that postoperative 3 months(P〈0.05). Conclusion Interventional occlusion has ideal efficacy for PFO patients complicated with anomalous embolization, which can improve the blood flow status of the brain and control the degree of migraine.
作者 李阳 刘媛 LI Yang;LIU Yuan(Xianyang Hospital Affiliated to Yan'an University,Xianyang 712000,China)
出处 《临床医学研究与实践》 2018年第17期28-29,共2页 Clinical Research and Practice
关键词 卵圆孔未闭(PFO) 反常栓塞 介入封堵 patent foramen ovale (PFO) anomalous embolization interventional occlusion
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