摘要
目的探讨急性脑梗死患者血清钾离子和血清镁离子水平变化及其临床意义,为患者的临床治疗提供参考。方法选择该院2014年3月至2016年3月入院治疗的急性脑梗死患者100例作为研究对象,按照患者病情将进展性脑梗死患者50例作为观察组,非进展性脑梗死患者50例作为对照组,对所有患者治疗前、治疗中以及治疗后的不同阶段血清钾离子以及血清镁离子进行检测,并在同一时期与对照组进行比较;比较两组患者不同时期神经功能缺损评分。结果观察组患者入院后第2天,血清钾离子水平低于对照组患者,差异有统计学意义(P<0.05);观察组患者治疗2周和出院时的血清钾离子与对照组比较,差异无统计学意义(P>0.05)。观察组患者在入院后第2天,血清镁离子水平低于对照组患者,差异有统计学意义(P<0.05);观察组患者治疗2周和出院时的血清镁离子与对照组比较,差异无统计学意义(P>0.05)。观察组患者入院第2天和治疗2周时,神经功能缺损评分显著高于对照组,差异有统计学意义(P<0.05);出院时两组患者神经缺损评分比较,差异无统计学意义(P>0.05)。结论血清钾离子及血清镁离子的水平与急性脑梗死患者病情进展密切相关,患者进行血清钾离子及血清镁离子的检测可以作为患者病情和预后情况的重要参考标准。
Objective To investigate the changes of serum potassium and serum magnesium ion concentration in patients with acute cerebral infarction and its clinical significance,and to provide reference for the clinical treatment of patients.Methods One hundred patients with acute cerebral infarction who were hospitalized from March 2014 to March 2010 were enrolled in this study.Fifty patients with progressive cerebral infarction were treated as observation group and 50 patients with non-progressive cerebral infarction were treated as control group.Serum potassium and serum magnesium were measured before,during and after treatment in all patients.Potassium and magnesium were compared between the two groups.Scores of evaluation of nerve function defect were also compared between the groups.Results Serum potassium of the patients in the observation group at second day was significantly lower than that of control group（P〈0.05）,while,it had no significance between the two groups two weeks after treatment and at the time of discharge（P〈0.05）.Serum magnesium of the patients in the observation group at second day was significantly lower than that of control group（P〈0.05）,while,it had no significance between the two groups two weeks after treatment and at the time of discharge（P〈0.05）.Scores of evaluation of nerve function defect in observation group in the second day and two week after treatment were significantly higher than that of control group（P〈0.05）,while it had no statistical significance at the time of discharge（P〈0.05）.Conclusion Serum potassium and serum magnesium levels are closely related to the progression of patients.Therefore,the detection of serum potassium and serum magnesium can be used as an important reference standard for patient progression and prognosis.
作者
李祥坤
LI Xiangkun(Department of Clinical Laboratory,Suining Central Hospital,Suining,Sichuan 629000,Chin)
出处
《检验医学与临床》
CAS
2018年第14期2123-2125,共3页
Laboratory Medicine and Clinic
关键词
脑梗死
钾
镁
双抗体夹心法
免疫比浊法
cerebral infarction
potassium
magnesium
double-antibody sandwich
immunoturbidime
