摘要
目的分析单纯主动脉瓣病变的老年患者主动脉瓣置换术后人工瓣膜-患者不匹配(PPM)现象及PPM对术后早期心功能及左心室重构的影响。方法回顾性分析2016年1~12月我院连续134例单纯主动脉瓣病变行主动脉瓣置换术65岁以上患者的临床资料,其中男73例、女61例,年龄65~79(69.7±3.6)岁。分析他们的临床及超声心动图数据,有效瓣口面积指数(EOAI)≤0.85 cm2/m2定义为PPM。对比主动脉瓣狭窄与主动脉瓣关闭不全患者术后PPM发生率,并对比机械瓣与生物瓣术后效果。结果 80例主动脉瓣狭窄患者中有26例发生PPM(发生率32.5%),54例主动脉瓣关闭不全患者中7例发生PPM(发生率13.0%),差异具有统计学意义(P<0.05)。重度PPM 8例(发生率6.0%),1例患者术后早期死亡。结论单纯主动脉瓣反流行主动脉瓣置换术后PPM的发生率低于主动脉瓣狭窄的患者。
Objective To analyze the incidence of valve prosthesis-patient mismatch（PPM） and ventricular remodeling of elderly patients after aortic valve replacement（AVR）. Methods We retrospectively analyzed the clinical data of 134 patient aged over 65 years who underwent AVR for the aortic stenosis or regurgitation at our hospital between January 2016 and December 2016. There were 73 males and 61 females aged 69.7±3.6 years ranging from 65-79 years. The clinical and ultrasound cardiography data were evaluated. PPM was defined as an effective orifice area index（EOAI） of ≤0.85 cm^2/m^2. The incidence of PPM and the left ventricular remodeling after surgical AVR in the patients with aortic stenosis and aortic regurgitation was analyzed, and the outcomes of aortic valve mechanical prosthesis and aortic valve bioprosthesis were compared. Results The incidence of PPM was 32.5% in aortic stenosis and 13.0% in aortic regurgitation（P〈0.05）. One patient died in the early post-operation, and the incidence of severe PPM was 6.0%.Conclusion The incidence of PPM after AVR in the patients with aortic regurgitation is less than that in the patients with aortic stenosis.
作者
张兴
王巍
ZHANG Xing;WANG Wei(Department of Cardiovascular Surgery,Cardiovascular Institute and Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100037,P.R.China)
出处
《中国胸心血管外科临床杂志》
CAS
CSCD
2018年第8期707-710,共4页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
