摘要
目的鼓室内注射钆造影剂后,行内耳三维快速液体衰减反转恢复核磁共振(three-dimensional fluid-at-tenuated inversion recovery magnetic resonance imaging,3D-FLAIR MRI)扫描,进行外淋巴间隙MRI评分,研究临床疑似诊断梅尼埃病者内耳积水的阳性率,并探讨其对梅尼埃病的诊断价值。方法通过详实病史资料收集,对符合梅尼埃病疑似诊断标准的12例患者进行双侧鼓室内注射钆造影剂,24小时后进行内耳3D-FLAIR MRI检查,对检查结果进行分析、总结。结果 3D-FLAIR MRI显示内耳外淋巴间隙高信号、内淋巴间隙低信号,根据外淋巴间隙MRI评分方法及诊断标准,50%(6/12)显示积水征象,该6例患者随访均出现满足临床确诊的梅尼埃病症状。结论疑似诊断梅尼埃病患者应动态行相关听力学检查,有条件可行内耳造影,进一步佐证。
Objective Using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging （3D-FLAIR MRI） with intratympanic gadolinium injection, images of the perilymph space were scored for endolym-phatic hydrops in cases of suspected Meniere＇s disease to investigate its diagnostic value in Meniere＇s disease. Methods Diluted gadopentetate dimeglumine was injected via the tympanic membrane bilaterally in 12 patients suspected of hav-ing Meniere＇s disease. After 24 hours, inner ear 3D-FLAIR MRI was performed and results were analyzed. Results Gad-olinium contrast agent was seen distributed in the perilymphatic space with perilymph enhancement on 3D-FLAIR MRI, allowing differentiation between the perilymphatic and endolymphatic spaces. Based on perilymph MRI diagnostic scor-ing, 50% of the patients were categorized as having endolymphatic hydrops, who were followed and eventually diag-nosed with confirmed Meniere＇s disease. Conclusion Patients suspected of having Meniere＇s disease should receive hear-ing monitoring, while inner ear 3D-FLAIR MRI, when deemed appropriate, may facilitate early diagnosis and treatment.
作者
肖恒
王海霞
毛竹
周枫
叶胜难
陈曦
XIAO Heng;WANG Haixia;MAO Zhu;ZHOU Feng;YE Shengnan;CHEN Xi(Department of Otolaryngology-Head and Neck Surgery,First Affliated Hospital of Fujian Medical University;Department of Otolaryngology-Head and Neck Surgery,The Affiliated People’s Hospital of Fujian University of Traditional Chinese Medicine)
出处
《中华耳科学杂志》
CSCD
北大核心
2018年第3期285-289,共5页
Chinese Journal of Otology
基金
福建省卫计委医学创新课题(2014-CX-24)
福建省科技厅对外合作项目(2015I0002)~~
关键词
疑似诊断
梅尼埃病
鼓室内钆造影
磁共振成像
Suspected Diagnosis
Meniere＇s Disease
Intratympanic Gadolinium Contrast
Magnetic Reso-nance Imaging
