摘要
目的对比分析内镜黏膜下剥离术(ESD)联合前哨淋巴结(SLN)活检术与根治性切除治疗早期胃癌的效果。方法对2010年3月—2014年10月收治的92例早期胃癌患者的临床资料进行回顾性分析。根据手术方式的不同分为A组和B组,每组46例。A组给予ESD联合SLN活检术治疗,B组给予根治性切除治疗。比较两组术后1、3年复发率、术后3年生存率、住院时间、术中出血量以及并发症的发生情况。结果两组术后1、3年复发率及术后3年生存率比较差异无统计学意义(P>0.05)。A组住院时间和术中输血量均少于B组(P<0.01)。两组并发症总发生率比较差异无统计学意义(P>0.05)。结论 ESD联合SLN活检术与根治性切除治疗早期胃癌的效果相当,但ESD联合SLN活检术治疗可缩短住院时间、减小手术创伤。
Objective To compare effect of endoscopic submucosal dissection（ ESD） combined with sentinel lymph node（ SLN） biopsy and radical resection in treatment of patients with early gastric cancer. Methods Clinical data of 92 patients with early gastric cancer admitted during March 2010 and October 2014 was retrospectively analyzed,and the patients were divided into group A and group B（ n = 46 for each group） according to different surgical methods.Group A was treated with ESD combined with SLN biopsy,while group B was treated with ESD combined with radical resection. Recurrence rates in postoperative 1 stand 3 rdyears,survival rate in postoperative 3 rdyear,hospital stay,intraoperative volume of blood loss and incidence rate of complications were compared in two groups. Results There were no significant differences in recurrence rates in postoperative 1 stand 3 rdyears and survival rate in postoperative 3 rdyear between two groups（ P〉0. 05）. Values of hospital stay and intraoperative volume of blood transfusion in group A were less than those in group B（ P〈0. 01）. There was no significant difference in the total incidence rate of complications between two groups（ P〉0. 05）. Conclusion ESD combined with SLN biopsy may achieve similar effect with that by radical resection in treatment of patients with early gastric cancer,while ESD combined with SLN biopsy may shorten length of hospital stay and reduce degree of surgical trauma.
作者
姬乐
李小宝
高永涛
刘涛
白浪
Jl Le;LI Xiao-hao;GAO Yong-tao;LIU Tao;BAI Lang(Department of General Surgery,Affiliated Hospital of Yanhn University,Yanan,Shaanxi 716000,China)
出处
《解放军医药杂志》
CAS
2018年第6期10-13,共4页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
陕西省教育厅自然科学研究项目(2013JK0782)
关键词
内镜黏膜下剥离术
前哨淋巴结活组织检查
胃肿瘤
疗效比较研究
Endoscopic submueosal dissection
Sentinel lymph node biopsy
Stomach neoplasms
Comparativeeffectiveness research
