摘要
目的研究分析氟西汀治疗酒精依赖戒断后情感障碍的效果。方法收集2014年10月—2017年10月期间该院收治的酒精依赖戒断后情感障碍患者83例作为研究对象,按照入院先后顺序将这83例酒精依赖戒断后情感障碍患者分为对照组(n=42),观察组(n=41);对照组的42例患者接受阿米替林治疗,观察组的41例患者接受氟西汀治疗,观察对比两组患者的治疗效果、焦虑、抑郁评分以及不良反应。结果观察组41例的患者临床治疗总有效率为92.86%,明显高于对照组42例患者的临床治疗总有效率为83.33%(χ~2=3.541 3,P=0.000 0);治疗前两组患者的SAS、SDS评分差异无统计学意义,接受治疗后两组患者的SAS、SDS评分均明显降低,观察组明显低于对照组;观察组患者与对照组患者在接受治疗过程中均出现不同程度头晕、口干、心动过速以及嗜睡等不良反应,均能够耐受,在治疗第4周观察组患者的TESS评分为(1.52±0.54)分,明显低于对照组患者的TESS评分(1.87±0.69)分,差异有统计学意义(P<0.05)。结论氟西汀治疗酒精依赖戒断后情感障碍的效果显著,治疗有效率高,能够改善患者不良情绪,不良反应低,安全性高。
Objective To research and analyze the effect of fluoxetine in treatment of emotional disorder after the Alcohol dependence abstinence. Methods 83 cases of patients with emotional disorder after the Alcohol dependence abstinence in our hospital from October 2014 to October 2017 were selected as the research objects, and divided into two groups, the control group with 42 cases were treated with amitriptyline, while the observation group with 41 cases were treated with fluoxetine, and the treatment effect, anxiety, depression and toxic and side effects of the two groups were observed and compared. Results The total clinical treatment effective rate in the observation group was obviously higher than that in the control group（92.86% vs 83.33%）,（χ^2=3.541 3, P=0.000 0）, and the differences in the SAS and SDS scores between the two groups before treatment were not obvious, after treatment, the indexes in the two groups obviously decreased, and the indexes in the observation group were obviously lower than those in the control group, and the adverse reactions such as different degrees of dizziness, dryness, tachycardia, and lethargy in treatment course could be resistant, in the fourth week after treatment, the TESS score of patients was obviously lower than that in the control group, [（1.52±0.54）points vs（1.87±0.69）points], and the difference was statistically significant（P〈0.05）. Conclusion The effect of fluoxetine in treatment of emotional disorder after the Alcohol dependence abstinence is obvious, and the high treatment effective rate can obviously improve the adverse emotions with low toxic and side effects and high safety.
作者
王林青
WANG Lin-qing(Department of Psychiatry,Miyun District Mental and Health Prevention Institution,Beijing,101501 China)
出处
《系统医学》
2018年第7期26-28,共3页
Systems Medicine
关键词
氟西汀
酒精依赖戒断
情感障碍
效果
Fluoxetine
Alcohol dependence abstinence
Emotional disorder
Effect
