摘要
目的 探讨首剂不同剂量地西泮治疗癫痫持续状态的临床效果.方法 选取阜新市第五人民医院2011年1月-2017年1月收治的癫痫持续状态患者80例,按照地西泮首剂给药剂量的不同分为A组和B组,A组给予地西泮20 mg静脉注射,B组给予地西泮10 mg静脉注射.结果 总有效率A组为88.1％、B组为65.8％,差异有统计学意义（P＜0.05）.癫痫状态得到控制时间A组（16.73±3.72）min、B组（21.50±4.25）min,差异有统计学意义P＜0.05）.两组均未出现低血压、呼吸抑制等不良反应.结论 给予地西泮20 mg首剂剂量治疗癫痫持续状态,起效更快,疗效更好,且未见严重不良反应发生.
Objective The aim of the study is to investigate the clinical efficacy of diazepam with different doses on the treatment of epilepsy. Methods A total of 80 patients with epilepsy status were recruited from Fuxin Fifth People＇s Hospital between January 2011 and January 2017. According to different doses of diazepam, all patients were grouped into A group （treated with 20 mg diazepam, intravenous injection） and B group （treated with 10 mg diazepam, intravenous injection）. Results The total effective rate in A group was 88.1%, B group was 65.81%, and the difference is significant （P〈0.05）. The time used in controlling epilepsy was （16.73±3.72） min in A group, and （21.50±4.25） min in B group （P〈0.05）. Hypotension, respiratory repression, and other adverse reaction did not occurred. Conclusion Administration of diazepam at 20 mg, intravenous injection for epilepsy patients has fast effect, good curative effect and no adverse reaction.
出处
《中国实用乡村医生杂志》
2017年第11期54-56,共3页
Chinese Practical Journal of Rural Doctor
