摘要
【目的】比较可调钠曲线透析和序贯透析治疗终末期肾病（EsRD）伴顽固性高血压（RH）的效果及对左心室功能的影响。【方法】40例ESRD伴RH患者随机分为可调钠曲线组（A组）和序贯透析组（B组），每组各20例。比较透析前和透析3个月后两组C反应蛋白（CRP）、白介素6（IL-6）、肿瘤坏死因子α（TNFα）、血管紧张素Ⅱ（AngⅡ），收缩压（SBP）、舒张压（DBP）、平均动脉压（MAP）、左室射血分数（LVEF）、左心室心肌质量指数（LV-MI）、左心室舒张末内径（LVEDd）差异。【结果】A组透析后AngⅡ、CRP、IL-6、TNF-α水平，MAP、SBP、DBP及LVMI、LVEDd均低于，LVEF高于B组，且两组比较差异均有显著性（P〈0．05）。【结论】可调钠曲线透析患者RH控制效果、左心室功能改善情况优于序贯透析治疗。
[Objective]To compare the effects of adjustable sodium curve and sequential dialysis on the treatment of end-stage renal disease （ESRD） with refractory hypertension （RH） and their effects on left ventricular function. [Meth- odslA total of 40 cases of patients with ESRD and RT were randomly divided into an adjustable sodium curve group （A group） and a sequential dialysis group （B group）, with 20 cases in each. The levels of C reactive protein （CRP）, IL-6, TNF- α, angiotensin II （Ang II）, systolic blood pressure （SBP）, diastolic blood pressure （DBP）, mean arterial pressure （MAP）, left ventricular ejection fraction （LVEF）, left ventricular mass index （LVMI）, and left ventricular end diastolic diameter （LVEDd） in both groups were determined before dialysis and 3 months after dialysis. [ResultslAfter dialysis, the levels of Ang II, CRP, IL-6, TNF-α ; MAP, SBP, DBP, LVMI, and LVEDd of group A were lower than those of group B （ P 〈0.05）. The LVEF of group A was higher than that of group B （ P 〈0.05）. [Conclusion] The curative effects of ESRD with RH and the improvements of left ventrieular function in patients receiving adjustable sodium curve are superior to sequential dialysis treatment.
作者
王润蕾
WANG Run-lei(The People＇s Hospital of Chongzhou, Shichuan Province ,611230)
出处
《医学临床研究》
CAS
2018年第6期1092-1094,共3页
Journal of Clinical Research
关键词
肾病/治疗
高血压
肾透析/方法
心室功能
左
Nephrosis/TH
Hypertension
Renal Dialysis/MT
Ventricular Function
Left
