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M蛋白与周围神经病变

Monoclonal protein and peripheral neuropathy
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摘要 M蛋白是由单克隆浆细胞分泌的单克隆免疫球蛋白,血中含有大量的单克隆免疫球蛋白又称为副蛋白血症。临床上,副蛋白血症与周围神经病变关系密切。本文从血液学角度,总结了M蛋白相关周围神经病变的发病机制、常见临床情况、诊断以及治疗,以期加深理解、为临床诊疗提供帮助。 Monoclonal protein is produced by monoclonal plasma cells. When much monoclonal protein emerges in blood,it is named as paraproteinemia. Clinically, paraproteinemia is closely related to peripheral neuropathy（ PN）. This article has reviewed the pathogenesis,general disorders,diagnosis and treatment of PN in order to offer help in clinical practice.
作者 郝渊渊 孙婉玲 Hao Yuanyuan;Sun Wanling(Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China)
机构地区 首都医科大学宣武医院血液科
出处 《首都医科大学学报》 CAS 北大核心 2018年第3期344-348,共5页 Journal of Capital Medical University
关键词 单克隆免疫球蛋白 周围神经病变 副蛋白血症 monoclonal immune globulin protein；peripheral neuropathy；paraproteinemia
分类号 R741 [医药卫生—神经病学与精神病学]
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首都医科大学学报
2018年 第3期

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