摘要
目的上消化道癌筛查对其早发现、早诊断及早治疗具有重要意义。本研究分析了国内外上消化道癌筛查的效果及经济学评价,总结了目前上消化道癌筛查的开展现状和不同筛查方案的经济学评价结果。方法应用PubMed、中国知网和万方数据库检索系统,以"上消化道癌、胃癌和食管癌筛查"为主体关键词,联合"效果和结果"、"成本-效果和经济学评价"等关键词,检索2006-01-2017-11相关文献641篇。纳入标准:(1)上消化道癌筛查方法、方案和相关结果;(2)上消化道癌筛查的经济学评价。排除标准:(1)重复报告;(2)存在设计缺陷;(3)不符合研究目的。根据纳入标准与排除标准,符合分析的文献37篇。结果目前上消化道癌的筛查项目主要存在于亚洲东部,筛查方法主要选用内镜检查加指示性活组织检查,筛查人群年龄40~60岁,其中我国上消化道癌的检出率约为0.6%。多项卫生经济学评价研究证明,目前开展的上消化道癌筛查项目均符合成本-效果原则。结论我国是上消化道癌发病率较高的国家之一,有必要进一步研究上消化道癌筛查相关方案的效果和经济性,以及进一步推广筛查项目。
OBJECTIVE The screening of upper gastrointestinal carcinoma is important for early detection,early diagnosis and early treatment of upper digestive tract carcinoma.This article analyze the effects and economic evaluations of upper gastrointestinal cancer screening programmes conducted both at home and abroad,to summarize the implementation of the upper digestive cancer screening and outcomes of different screening programmes.METHODS The literature were retrieved in PubMed,CNKI and Wanfang Data from 2006-01-2017-11.The keywords were＂upper gastrointestinal tract cancer/gastric cancer/esophageal gastric cancer screening＂,joint＂effect,results,cost-effectiveness evaluation/economics＂.Totally 641 articles was detected.The inclusion criteria：（1）The main methods,strategies and results of various screening programs for upper digestive tract cancer.（2）Cost-effectiveness and cost-benefit analysis of various screening programs for upper digestive tract cancer.The exclusion criteria：（1）Repeated report.（2）Existing design flows.（3）Not consistent with the purpose of the study.Totally 37 articles were included and analysed.RESULTS The upper gastrointestinal tract cancer screening programmes mainly exist in eastern Asia.The main screening method is the endoscopy with indicative biopsies,and the range of screened people age is roughly between 40 to 60 years old.The detection rate is about 0.6%.A number of health economics evaluation studies have found that the upper gastrointestinal cancer screening program in eastern Asia is in line with the cost-effectiveness principle.CONCLUSIONS China is one of the countries with higher incidence of upper gastrointestinal cancer and higher fatality rate.It is necessary to carry out large-scale cancer screening programs and further improve the screening of upper digestive tract cancer.
作者
邵雨辰
张楠
王家林
孙晓杰
SHAO Yu-chen;ZHANG Nan;WANG Jia-lin;SUN Xiao-jie(School of Health Care Management ,Shandong University ,Key Laboratory of Health Economics and Policy Research, National Heath and Family Planning Commission, Jinan 250012 ,P. R. China;Departrnent of Science and Education, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan 250117, P. R. China)
出处
《中华肿瘤防治杂志》
CAS
北大核心
2018年第9期681-684,共4页
Chinese Journal of Cancer Prevention and Treatment
基金
美国中华医学基金会公开竞争项目(13-160)
关键词
上消化道癌
筛查
效果
经济学评价
upper gastrointestinal cancer
screening
effect
economic evaluation
