摘要
目的探讨猪小肠黏膜下层脱细胞基质(porcine small intestine submucosa,SIS)补片对比轻量聚丙烯(polypropylene mesh,PP)补片在腹股沟疝Lichtenstein修补术中应用的安全性和短期疗效。方法回顾性分析2012年1月至2015年8月,中山大学附属第一医院使用SIS补片和轻量PP补片做单侧腹股沟疝Lichtenstein修补术的连续男性病例资料,SIS组和PP组分别纳入64例,比较2组患者手术安全性和短期疗效。结果 SIS组与PP组在术后24 h疼痛评分、发热、伤口脂肪液化、血清肿、尿潴留、睾丸并发症发生率比较,差异无统计学意义(P均>0.05)。2组均无手术部位感染和血肿发生病例。2组均无复发病例。SIS组在术后慢性疼痛(14.1%比15.6%,?2=0.062,P=0.804),术后腹股沟区不适感(12.5%比17.2%,?2=0.556,P=0.456),异物感(3.1%比4.7%,P=1.000)均低于PP组,但2组差异无统计学意义(P均>0.05)。2组在术后均无明显射精疼痛或障碍,无睾丸萎缩。PP组有2例(3.1%)患者出现手术侧睾丸肿大。结论 SIS补片对比轻量PP补片在腹股沟疝Lichtenstein修补术中应用的安全性和短期疗效是相当的,其长期疗效仍有待进一步观察。
Objective The purpose of this study was to investigate the safety and efficacy of porcine small intestine submucosa（SIS） mesh versus Lightweight polypropylene（PP） mesh in Lichtenstein repair of inguinal hernia. Methods From January 1 2012 to August 31 2015, the consecutive male patients of unilateral inguinal hernia undergoing Lichtenstein repair using SIS mesh and lightweight PP mesh in the First Affiliated Hospital of Sun Yat-Sen University were analyzed retrospectively. SIS group and PP group were enrolled in 64 patients respectively. The safety and short-term efficacy of the two groups were compared. Results There were no significant differences in pain score at 24 hours after operation, fever, wound fat liquefaction, serum swelling, urinary retention, testicular complications between the SIS group and the PP group（all P〉0.05）. There were no surgical site infection and hematoma cases in two groups. No recurrence occurred in two groups. Although the severity of postoperative chronic pain（14.1% vs 15.6%, X2=0.062, P=0.804）, postoperative groin discomfort（12.5% vs 17.2%, X2=0.556, P=0.456）, foreign body sensation（3.1% vs 4.7%, P=1.000） in the SIS group were lower than those in the PP group, but there was no statistically significant difference between the two groups（all P〉 0.05）. There were no obvious ejaculatory pain or obstruction and testicular atrophy occurred in two groups. There were two cases（3.1%） of testicular swelling in PP group. Conclusions The safety and short-term efficacy of SIS mesh compared with light PP mesh in Lichtenstein repair of inguinal hernia are comparable, but the long-term efficacy remains to be further observed.
作者
戴伟钢
左继东
谭进富
袁玉杰
袁凯涛
冯伟东
赵琼云
谭敏
Dai Weigang;Zuo Jidong;Tan Jinfu;Yuan Yujie;Yuan Kaitao;Feng Weidong;Zhao Qiongyun;Tan Min.(Department of Gastrointestinal Surgery, Hernia and Abdominal Wall Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China)
出处
《中华疝和腹壁外科杂志（电子版）》
2018年第3期199-203,共5页
Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition)
基金
广东省公益研究和能力建设专项资金资助项目(2016A010103038)
国家自然科学基金-青年基金资助项目(81602660,81401307)
关键词
疝
腹股沟
疝修补术
生物补片
聚丙烯补片
并发症
复发
Hernia
inguinal
Herniorrhaphy
Biological mesh
Polypropylene mesh
Complication
Recurrence
