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Chemotherapy drugs induce pyroptosis through caspase-3-dependent cleavage of GSDME 被引量:17

Chemotherapy drugs induce pyroptosis through caspase-3-dependent cleavage of GSDME
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摘要 Chemotherapy drugs can induce cancer cell death via a series of regulated cell death(RCD)pathways including apoptosis and regulated necrosis(Vanden Berghe et al.,2014).Characterized by activation of the caspase family of cystine proteases,the occurrence of apoptosis leads to cell shrinkage and formation of apoptotic bodies. Chemotherapy drugs can induce cancer cell death via a series of regulated cell death(RCD)pathways including apoptosis and regulated necrosis(Vanden Berghe et al.,2014).Characterized by activation of the caspase family of cystine proteases,the occurrence of apoptosis leads to cell shrinkage and formation of apoptotic bodies.In vivo。
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2018年第6期739-740,共2页 中国科学(生命科学英文版)
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