摘要
目的探讨三维-数字减影血管造影技术在肝动脉化学治疗栓塞术中诊断及引导作用的临床应用价值。方法收集2017年3月至2017年5月肝癌患者为治疗组采取三维-数字减影血管造影术造影引导；另外选取肝癌患者为对照组行普通二维-数字减影血管造影术造影；观察术中血管及肿瘤病灶显影情况，分别统计两组患者手术全程曝光剂量（CAK，单位：mGy）、单位面积累积照射强度（DAP，单位：mGy／cm^2）及造影剂用量（ml）。两组患者全部由相同的高年资医生及技师操作。计量资料的比较采用t检验，计数资料的比较采用x^2检验。结果两组各收集到20例患者资料。治疗组全部患者肿瘤位置及靶血管结构、走形显影清晰；对照组肿瘤显影明确17例，靶血管结构显影清晰16例；CAK均值治疗组低于对照组，分别为（554．11±38．87）mGy、（644．53±26．70）mGy；DAP均值治疗组低于对照组分别为（125．25±7．54）mGy／cm^2、（143．49±6．18）mGy／cm^2，两组比较P值均〈0．05，差异均有统计学意义；两组患者造影剂用量均值治疗组低于对照组，分别为（64．42±3．92）ml、（70．79±4．47）ml，两组比较，P〈0．05，差异有统计学意义。结论三维一数字减影血管造影技术在肝动脉化学治疗栓塞术中能提供有效的诊断及引导信息，能有效减少手术射线曝光剂量及射线累及照射强度，对肝癌介入栓塞治疗有较高临床应用价值。
Objective To explore the clinical value of 3D-DSA technology in the diagnosis and treatment guidance of hepatic artery chemoembolization. Methods Liver cancer patients in the treatment groups were collected to receive 3D-DSA imaging guidance at the Affiliated Hospital of Xuzhou Medical University between March and May 2017. In addition, routine 2D-DSA imaging was selected for treatmentreceived group. Intra-operative blood vessels and tumor-like lesions were observed. The total exposure dose （CAK, unit mGy）, cumulative irradiation intensity per unit area （DAP, unit mGy.cm^2） and dosage of contrast agent （ml） were calculated separately for two groups of patients. The same senior physicians and technicians operated both groups of patients. Comparisons of measurement were analyzed by t-test and chi-square test was used for count data. Results Data of twenty patients were collected from the two groups. Tumor location, target vessels structure and shape of development were clear in all patients in the treatment group. The control group had 17 cases of tumor development and the target vascular structure was clear in 16 cases. CAK mean treatment group was lower than control group （554.11 ±38.87） mGy and （644.53± 26.70） mGy, and DAP mean treatment group was lower than the control group （125.25 ± 7.54） mGy · cm^2 and （143.49 ± 6.18） mGy · cm^2. The two groups were compared （P value 〈 0.05）, and the differences were statistically significant. The mean dose of contrast agent in the two groups were lower than control group （64.42 ±3.92） ml, （70.79 ± 4.47） ml, and the differences between the two groups were statistically significant （P 〈 0.05）. Conclusion 3D-DSA imaging technology can provide effective diagnosis and guidance in the treatment of hepatic artery chemoembolization. It can effectively reduce the radiation exposure dose and radiation intensity, and it is of high clinical value for interventional embolization of liver cancer.
作者
柳昂
许伟
徐浩
王勇
赵红兰
沙俊诚
顾玉明
Liu Ang;Xu Wei;Xu Hao;Wang Yong;Zhao Honglan;Sha Juncheng;Gu Yuming(Department of Interventional Radiography, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China)
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2018年第6期436-440,共5页
Chinese Journal of Hepatology
关键词
血管造影术
数字减影
肝动脉
曝光剂量
Angiography
digital subtraction
Hepatic Artery
Exposure dose
