摘要
目的：探究中医联合介入治疗肝癌的疗效及其CT影像学变化分析。方法：选择医院收治的98例肝癌患者为研究对象,根据患者的入院时间,分为观察组50例和对照组48例,观察组使用中医联合介入治疗,对照组仅使用介入治疗。比较两组患者治疗前后MSCT检查的肿瘤容积、个数和转移情况。比较两组患者治疗前后的肝功能生化指标变化以及两组治疗后的并发症发生情况。结果：两组治疗前MSCT检查,肿瘤容积、肿瘤个数和肝外转移患者数无明显差异,不具统计学意义（P〉0.05）。治疗后,两组的肿瘤容积、肿瘤个数跟治疗前相比差异明显,有统计学意义。治疗后,观察组患者的肿瘤容积、肿瘤个数和肝外转移患者数跟对照组相比改善更明显,差异有统计学意义（P〈0.05）。治疗前,两组的ALT、ALB、AST、AKP、AFP和GLD六项指标无明显差异（P〉0.05）。治疗后,两组的ALT、ALB、AST、AKP、AFP和GLD六项指标跟治疗前比较,都有明显改善,差异具有统计学意义（P〈0.05）。治疗后,比较两组的肝功能指标改善情况,观察组明显好于对照组（P〈0.05）。两组患者治疗后的并发症发生情况比较,观察组出现3例恶心、1例发热、2例上腹不适;对照组出现7例恶心、8例发热和6例上腹不适,观察组的并发症发生率跟对照组相比更低,差异有统计学意义（P〈0.05）。对比两组肝癌TACE术后1周及术后2月的CT复查结果,显示观察组的治疗效果更好。结论：对原发性肝癌患者行中西医结合治疗能明显改善患者症状,减少并发症的发生,治疗效果安全可靠。
Objective： To explore the curative effect and CT imaging analysis of interventional therapy of liver cancer with Chinese medicine. Methods ： Ninety - eight cases of liver cancer patients as the research objects, according to the hospitalization time, were divided into the observation group 50 cases and the control group 48 cases. The observation group used traditional Chinese medicine combined with interventional therapy and the control group only used interven- tional therapy. The volume, number and metastasis of MSCT were compared between the two groups before and after treatment. The biochemical parameters of liver function and the incidence of complications in the two groups were com- pared between the two groups before and after treatment. Results： There was no significant difference in tumor volume, tumor number or extrahepatic metastasis between the two groups before treatment, and there was no statistical significance （P 〉 0. 05） in the MSCT examination. After treatment, the volume of tumor and the number of tumor in the two groups were significant compared with those before treatment. After treatment, the tumor volume, the number of tumor and the number of extrahepatic metastasis patients in the observation group improved more obviously compared with those of the control group, and the difference was statistically significant （ P 〈 0.05 ）. Before treatment, the two groups ＇ ALT, A, LB, AST, AKP, AFP and GLD were not significant（P 〉 0. 05）. After treatment, the two groups＇ ALT, A, LB, AST, AKP, AFP and GLD were significantly improved, and the difference was statistically significant （ P 〈 0.05 ）. The im- provement of liver function in the observation group was better than that in the control group （ P 〈 O. 05 ）. In the two groups after treatment, observation group had 3 cases of nausea, 1 case of fever, 2 cases of epigastric discomfort and the control group had 7 cases of nausea, 8 cases of fever and 6 cases of epigastric discomfort. The total incidence rate of com-
作者
丁国军
陈玉堂
何东
DING Guojun;CHEN Yutang;HE Dong(Department of Radiology, Zhejiang Cancer Hospital,Hangzhou 310022,Zhejiang,China;No. 117 Hospital of The People＇ s Liberation Army, Hangzhou 310013, Zhejiang, China)
出处
《中华中医药学刊》
CAS
北大核心
2018年第6期1465-1468,I0031,共5页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省医药卫生一般研究计划项目(2015KYB106)
关键词
中医
介入治疗
肝癌
CT影像学变化
traditional Chinese medicine
interventional therapy
liver cancer
CT imaging changes
