摘要
目的对比丙泊酚和依托咪酯应用在无痛人流手术中对患者苏醒后心理状态和药物安全性的应用价值。方法回顾性选取2016年1月-2017年8月本院行无痛人流手术患者320例,根据麻醉方法分为观察组和对照组,对照组麻醉方式采取芬太尼联合丙泊酚,观察组麻醉方式采取芬太尼联合依托咪酯,对比两组麻醉效果和临床安全性。结果观察组术中值MAP(85.49±13.11)mm Hg,HR(74.03±8.44)次/min,血氧饱和度(98.69±0.12)%;对照组术中值MAP(74.43±4.59)mm Hg,HR(65.21±4.19)次/min,血氧饱和度(95.44±0.42)%,组间对比差异有统计学意义(P<0.05)。观察组苏醒后正性情绪(35.56±3.41)分,负性情绪(22.17±1.56)分;对照组苏醒后正性情绪(28.59±1.83)分,负性情绪(27.49±3.34)分,组间对比差异有统计学意义(P<0.05)。观察组手术过程中发生恶心呕吐8例,呼吸抑制6例,肌痉挛8例,心动过缓1例;对照组手术过程中发生恶心呕吐9例,呼吸抑制4例,肌痉挛4例,心动过缓2例,组间对比差异无统计学意义(P>0.05)。结论依托咪酯复合芬太尼应用在无痛人流手术中麻醉效果确切,血流动力学更稳定,不会增加不良反应,减轻患者苏醒后负性心理压力,值得在临床推广应用。
Objective Comparison of the application value of propofol and etomidate in patients with painless abortion after resuscitation and psychological status of patients and drug safety. Methods 320 cases of patients with painless abortion surgery in January2016 to August 2017 in our hospital were retrospectively selected. According to the anesthesia methods, all cases were divided into observation group and control group. control group were anesthetized through propofol and fentanyl. Observation group were anesthetized through fentanyl combined with etomidate. Anesthetic effects and clinical safety were compared between two groups.Result The value MAP of the observation group was（85.49±13.11） mm Hg, HR was（74.03±8.44）/min, blood oxygen saturation was（98.69±0.12） %; In the control group, the MAP value was（74.43±4.59） mm Hg, HR was（65.21±4.19）, blood oxygen saturation was（95.44±0.42） %, and the differences between two groups were statistically significant（P〈0.05）. Positive emotions（35.56 ±3.41） and negative emotions（22.17 ±1.56） were observed in the observation group. In the control group, positive emotions were（28.59±1.83） points and negative emotions were（27.49±3.34） points, and the differences between two groups were statistically significant（P〈0.05）. In the observation group, 8 cases were observed to have nausea and vomiting during the operation, 6 cases were got respiratory depression, and 8 cases were observed having muscular spasm, and 1 case was observed having bradycardia. In the control group, there were 9 cases having nausea and vomiting, 4 cases having respiratory inhibition, 4 cases having muscle spasm, 2 cases having bradycardia, and there were no statistically significant differences between two groups（P〉0.05）. Conclusion Anesthesia effect about etomidate combined with fentanyl in painless abortion surgery is obvious and can get more stable hemodynamics. And it does not increase adverse reactions. And it can reduce negative psychological
作者
玛依努尔
Mayinuer(Maternity-Care Division,The Maternal and Child Health Hospital in Changji City, Xinjiang, Changji, 830002, Chin)
出处
《新疆医学》
2018年第4期377-379,共3页
Xinjiang Medical Journal
关键词
丙泊酚
依托咪酯
无痛人流
心理状态
Propofol
Etomidate
painless abortion
psychological status
