摘要
目的 探讨联合应用奥美拉唑、莫沙必利及膈肌生物反馈训练治疗反流性食管炎的长期疗效.方法 将50例反流性食管炎患者随机分为对照组与观察组,每组25例,对照组应用奥美拉唑联合莫沙必利治疗,观察组联合应用奥美拉唑、莫沙必利及膈肌生物反馈训练治疗.比较两组患者治疗前及治疗结束后3个月的反流症状积分、胃食管反流病相关生活质量量表（GERD-HRQL）积分及Zung氏焦虑量表评分改善情况.结果 治疗前两组反流症状积分、GERD-HRQL积分及Zung氏焦虑量表评分比较差异未见统计学意义（P〉0.05）;治疗结束后3个月两组上述指标均较治疗前明显改善,且观察组改善较对照组更为明显（P〈0.05）.结论 联合应用奥美拉唑、莫沙必利及膈肌生物反馈训练治疗可有效改善反流性食管炎的长期疗效.
Objective To bined with diaphragm biofeedback esophagitis were randomly divided investigate the long-term efficacy of omeprazole and mosapride corn- therapy on reflux esophagitis. Methods Fifty patients with reflux into control group and observation group, with 25 cases in each group.Patients in control group were treated with omeprazole and mosapride, and patients in observation group were treated with omeprazole and mosapride combined with diaphragm biofeedback. The improvement on reflux symptom score, GERD-HRQL score and Zung＇s anxiety scale score was compared between the two groups before treatment and 3 months after treatment. Results Before treatment, there was no statisti-cally significant difference in reflux symptom scores, GERD-HRQL integral and Zung＇s anxiety scale be-tween the two groups （P 〉 0. 05) ; all the above indexes in the two groups were significantly improved 3 months after treatment, and the improvement of observation group was more obvious than that of control group (P 〈 0. 05). Conclusions The combined application of omeprazole, mosapride and diaphragm biofeedback therapy can effectively improve the long-term curative effect of reflux esophagitis.
作者
田金亚
Tian Jinya(Department of Digestive, the First People＇s Hospital of Zhengzhou, Zhengzhou 450000, Chin)
出处
《中国实用医刊》
2018年第9期109-111,共3页
Chinese Journal of Practical Medicine
