摘要
目的探究LEEP刀宫颈锥切术结合术前术后应用重组α-2b干扰素栓治疗宫颈上皮内瘤变的临床效果。方法在该院2016年1月—2017年1月间收治的宫颈上皮内瘤变患者中选取127例作为研究对象,并随机分为观察组69例和对照组58例。对照组患者采取LEEP刀宫颈锥切术结合术后应用α-2b干扰素栓进行治疗,观察组患者采取LEEP刀宫颈锥切术结合术前术后应用α-2b干扰素栓进行治疗。对比两组患者术中出血情况、创面愈合所需时间。对比两组患者术后半年的临床疗效。结果对照组患者的总有效率(65.52%)要低于观察组患者的总有效率(92.75%)(χ~2=14.785 6,P<0.05)。结论 LEEP刀宫颈锥切术结合术前术后重组α-2b干扰素栓的治疗方式,对宫颈上皮内瘤变具有良好的治疗效果,值得在临床上广泛推广。
Objective To study the clinical effect of LEEP knife cervical conization combined with recombinant human interferon α-2 b suppository in treatment of cervical intraepithelial neoplasia. Methods 127 cases of patients with cervical intraepithelial neoplasia admitted and treated in our hospital from January 2016 to January 2017 were selected and randomly divided into two groups, the control group with 58 cases used the routine treatment, while the observation group used the LEEP knife cervical conization combined with recombinant human interferon α-2 b suppository before and after surgery, and the intraoperative bleeding situation and wound healing time were compared between the two groups, and the clinical curative effect in half a year after surgery was compared between the two groups. Results The total effective rate in the control group was lower than that in the observation group,（65.52% vs 92.75%）（χ^2=14.785 6,P〈0.05）. Conclusion The effect of LEEP knife cervical conization combined with recombinant Human Interferon α-2 b Suppository in treatment of cervical intraepithelial neoplasia is good, which is worth wide promotion in clinic.
作者
孔令敏
KONG Ling-min(Women Healtheare Department, Qufu Family Planning Service Center for Maternal and Child Health, Qufu, Shandong Province, 273100 China)
出处
《系统医学》
2018年第1期99-101,共3页
Systems Medicine
关键词
宫颈上皮内瘤变
LEEP刀宫颈切除术
重组α-2b干扰素栓
疗效
Cervical intraepithelial neoplasia
LEEP knife cervical conization
Recombinant human interferon α-2bsuppository
Curative effect
