摘要
雌激素和雌激素受体对海马依赖性高级功能情绪和认知相关的神经疾病具有极其重要的调节改善作用,因此,现将对其在抑郁症、精神分裂症和阿尔茨海默病中的调节作用进行综述,补充雌激素或选择性雌激素受体调节剂可能成为治疗这些疾病的新方法。
Estrogen and estrogen receptors play a vitally regulated role in hippocampus dependent advanced functional emotion and cognitive related diseases. Therefore, this paper reviews the regulation function of estrogen and its receptors in depression, schizophrenia and Alzheimer disease (AD). Supplementation of estrogen or selective estrogen receptor modulators may be a new method for the treatment of depression, schizophrenia and AD.
作者
梁梅丽
赵芳
高晓霞
Liang Meili;Zhao Fang;Gao Xiaoxia(Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, Chin;College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006. Chin)
出处
《神经疾病与精神卫生》
2018年第3期211-216,共6页
Journal of Neuroscience and Mental Health
关键词
雌激素
雌激素受体
海马依赖性
情绪
认知
综述
Estrogen
Estrogen receptor
Hippocampal dependent
Emotion
Cognition
Review