期刊文献+

丰富环境促进缺氧缺血性脑损伤神经可塑性的研究进展 被引量:12

Advance of Enriched Environment in Neural Plasticity post Hypoxic-ischemic Brain Damage(review)
下载PDF
导出
摘要 丰富环境是针对啮齿类动物习性制备的动物实验模型环境。缺氧缺血性脑损伤(HIBD)动物模型在丰富环境干预下,可增强突触可塑性,抑制神经元凋亡,调节细胞自噬,从而促进HIBD后神经功能修复。 The enriched environment is an artificial environment for animal models of rodentia. In the enriched environment, model animals may improve synaptic plasticity, inhibit apoptisis and regulate autophage after hypoxic-ischemic brain damage, that promote the recovery.
作者 吕富岩 张雷红 宫兆帅 苑爱云 Lü Fu-yan;ZHANG Lei-hong;GONG Zhao-shuai;YUAN Ai-yun(Department of Neurology Rehabilitation, Qingdao Women and Children's Hospital, Qingdao, Shandong 266034, Chin)
出处 《中国康复理论与实践》 CSCD 北大核心 2018年第5期509-512,共4页 Chinese Journal of Rehabilitation Theory and Practice
基金 山东省医药卫生科技发展计划项目(No.2015WS0352) 青岛市卫生科技计划项目(No.2015-WJZD091) 青岛市医药科研指导计划项目(No.2016-WJZD084) 青岛市医疗卫生优秀人才培养项目(No.2017.1-2019.12)~~
关键词 缺氧缺血性脑损伤 丰富环境 神经可塑性 凋亡 自噬 综述 hypoxic-ischemic brain damage enriched environment neural plasticity apoptisis autophage review
  • 相关文献

参考文献3

二级参考文献31

  • 1沈晓明.儿童脑科学研究的临床和教育学意义:从研究到应用[J].中国儿童保健杂志,2006,14(1):1-1. 被引量:39
  • 2陈燕惠,刘玲,陈敏榕,陈达光.早期干预对新生鼠脑神经生长相关蛋白表达及细胞凋亡的影响[J].实用儿科临床杂志,2007,22(14):1083-1084. 被引量:17
  • 3Rice JE,Vannucci RC,Brierley JB.The influence of immaturityon hypoxic-ischemic brain damage in the rat[J].Ann Neural,1981,9(2):131-141. 被引量:1
  • 4Couto RC,Carvalho EA,Pedrosa TM,Pedroso ER,Neto MC,Biscione FM.A 10-year prospective surveillance of nosocomial in-fections in neonatal intensive care units[J].Am J Infect Control,2007,35(3):183-189. 被引量:1
  • 5Liu YP,Bradley TL,Mustafa KB,Dempsey RJ,Vemuganti R.The potential of neural stem cells to repair stroke-induced braindamage[J].Acta Neuropathol,2009,117(5):469-480. 被引量:1
  • 6Rueger MA,Backes H,Walberer M,Neumaier B,Ullrich R,Si-mard ML,et al.Noninvasive imaging of endogenous neural stemcell mobilization in vivo using positron emission tomography[J].JNeurosci,2010,30(18):6454-6460. 被引量:1
  • 7Nithianantharajah J,Hannan AJ.Enriched environments,experi-ence-dependent plasticity and disorders of the nervous system[J].N Rev Neurosci,2006,7(9):697. 被引量:1
  • 8Maegele M,Lippert-Gruener M,Ester-Bode T,Garbe J,BouillonB,Neugebauer E.et al.Multimodal early onset stimulation com-bined with enriched environment is associated with reduced CNSlesion volume and enhanced reversal of neuromotor dysfunction af-ter traumatic brain injury in rats[J].Eur J Neurosci,2005,21(9):2406-2418. 被引量:1
  • 9Doi K, Sameshima H, Kodama Y,et al. Perinatal death and neurological damage as a sequential chain of poor outcome[ J]. J Matern Fetal Neo- natal Med, 2012, 25 (6):706-709. DOI: 10,3109/14767058.2011. 587061. 被引量:1
  • 10Kurinczuk J, White-Koning M, Badawi N. Epidemiolagy of nemata[ emephalopathy and hypoxic-ischaemic encephalopathy[J]. Early Hum1)ev,2010,86(6):329-338. DOI: 10.1016/j. earlhumdev. 2010.05. 010. 被引量:1

共引文献19

同被引文献97

引证文献12

二级引证文献42

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部