摘要
目的探讨应用消肿止痛汤湿敷治疗痔外剥内扎术后创面水肿、疼痛的疗效及安全性。方法选择在本院行外剥内扎术的152例痔病患者为研究对象,随机分为观察组(n=77)和对照组(n=75),两组术后均予相同的中药熏洗坐浴及口服非甾体类止痛药治疗。在此基础上,观察组采用消肿止痛汤湿敷,对照组采用50%硫酸镁湿敷法。湿敷治疗时间从术后第1 d至出院前1 d(观察组与对照组湿敷治疗时间分别为7~13 d及8~14 d),每日2次,每次30 min。比较两组疗效,术后中度及以上创面疼痛、创面水肿发生率以及不良反应发生率。结果观察组显效率高于对照组,差异有统计学意义(P<0.05);两组有效率差异无统计学意义(P>0.05);两组无效例数均为0。两组术后第1 d、第3 d中度及以上创面疼痛、创面水肿发生率差异均无统计学意义(均P>0.05)。术后第5 d、第7 d和出院前1 d,观察组中度及以上创面疼痛、创面水肿发生率均低于对照组,差异均有统计学意义(均P<0.05)。两组不良反应发生率差异无统计学意义(P<0.05)。结论消肿止痛汤湿敷可有效地减轻痔外剥内扎术后创面的水肿、疼痛,未增加不良反应发生率,可作为临床治疗选择之一。
Objective To investigate the effect and safety of Xiaozhongzhitong decoction wet compress on swelling and pain after dissection and ligation for hemorrhoid. Methods 152 patients who received dissection and ligation for hemorrhoid in our hospital were randomly assigned to treatment group(n = 77) and control group(n = 75). Both groups of patients were given postoperative sitz bath with Chinese herbs and oral non-steroidal analgesics. Patients in the treatment group received in addition Xiaozhongzhitong Decoction wet compress and the control group was treated with 50% magnesium sulfate wet compress. The wet compress was given from postoperative 1 d to the day before discharge, with 2 times a day and 30 min each time. The shortest treatment duration in the treatment group was 7 d and the longest duration was 13 d. The shortest treatment duration in the control group was 8 d and the longest 14 d. The efficacy, severity of edema and pain, and incidence of adverse reactions were compared between the two groups. Results The markedly effective rate of the treatment group was higher than that of the control group(P 〈 0.05), the difference of efficiency between the two groups was not statistically significant(P〉 0.05) and there was no ineffective case in the two groups. In terms of severity pain and wound edema moderate and above, there was no significant difference in the incidence between the two groups at postoperative 1 d and 3 d(P〉 0.05), but the rate in treatment group was lower than those of the control group at postoperative 5 d, 7 d and the day before discharge(P 〈 0.05). There was no significant difference in the incidence of adverse reactions between the two groups(P 〈 0.05). Conclusion Xiaozhongzhitong decoction wet compress can effectively reduce the severity of edema and pain after dissection and ligation for hemorrhoid. It does not increase the incidence of adverse reactions. It can be used as one of the clinical treatment options.
作者
乔东红
齐佳
鲁静
戴文竹
王凯
蔡姮婧
段宏岩
Qiao Donhong;Qi Jia;Lu Jing;Dai Wenzhu;Wang Kai;Cai Hengjing;Duan Hongyan.(Beijing Anorectal Hospital, Beijing, 100120, China)
出处
《结直肠肛门外科》
2018年第2期190-194,共5页
Journal of Colorectal & Anal Surgery
关键词
痔
外剥内扎术
消肿止痛汤
水肿
疼痛
hemorrhoids, Milligan-Morgan operation, Xiaozhongzhitong decoction, edema, pain