摘要
目的探讨磁共振（MR）高清扩散加权成像（RESOLVE DWI）对腮腺良恶性上皮性肿瘤的鉴别诊断价值。方法回顾性分析2015年7月至2017年10月郑州大学第一附属医院就诊经病理证实的106例单发腮腺上皮性肿瘤患者资料，术前均行常规MR及RESOLVEDWI检查。测量病变的表观扩散系数（ADC）均值，采用t检验分析腮腺上皮性肿瘤ADC值的差异，运用受试者工作特征（ROC）曲线评价ADC值的诊断价值。结果106例腮腺上皮性肿瘤中良性69例，恶性37例。良性肿瘤中多形性腺瘤和基底细胞腺瘤的ADC值为（1．47±0．16）×10^-3mm^2／s，腺淋巴瘤的ADC值为（0．83±0．19）×10^-3mm^2／s，恶性肿瘤的ADC值为（1．14±0．14）×10^-3mm^2／s，腺淋巴瘤的ADC值低于其余两组，三组两两比较，差异均有统计学意义（均P〈0．05）。以0．94×10。mm。／s≤ADC值≤1．28×10^-3mm^2／s为临界点判断腮腺恶性上皮性肿瘤，以病理结果为对照，其敏感度为81．1％，特异度为88．9％，与病理结果行一致性检验，kappa值为0．600。结论RESOLVEDWI鉴别诊断腮腺良恶性上皮性肿瘤具有一定参考价值。
Objective To investigate the diagnostic value of RESOLVE DWI in the evaluation of benign and malignant epithelial tumors of parotid gland. Methods A total of 106 patients in the First Affiliated Hospital of Zhengzhou University with epithelial tumors of parotid gland confirmed by pathology from July 2015 to October 2017 were retrospectively analyzed. All patients underwent preoperative routine MRI and RESOLVE DWI, the ADC average values were calculated, t test were used to compare the ADC values of benign and malignant epithelial tumors of parotid gland. Diagnostic performance of ADC value was compared using receiver operating characteristic （ROC）curves. Results All lesions were solitary, including 69 benign epithelial tumors and 37 malignant epithelial tumors. The mean ADC values of pleomorphic adenoma and basal cell adenoma, adenolymphoma and malignant epithelial tumors were （ 1.47±0. 16）×10^-3mm^2/s, （0. 83±0.19）×10^-3mm^2/s and（ 1.14±0. 14）×10^-3mm^2/s, the mean ADC value of adenolymphoma lower than the rest of the two groups, there were statistically significant differences among them （P〈0. 05）. Using 0. 94×10^-3mm^2〈ADC value≤1.28×10^-3mm^2/s as the critical value for diagnosing malignant epithelial tumors of parotid gland and comparing with pathological results, the result obtained had a sensitivity of 81.1%, specificity of 88. 9%. ADC value had high correlations compared with pathological results, kappa value was 0. 600. Conclusion RESOLVE DWI can be applied in differential diagnosis between benign and malignant epithelial tumors of parotid gland.
作者
文宝红
程敬亮
张会霞
张赞霞
王斐斐
薛康康
Wen Baohong;Cheng Jingliang;Zhang Huixia;Zhang Zanxia;Wang Feifei;Xue Kangkang(Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Chin)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2018年第17期1347-1351,共5页
National Medical Journal of China
基金
河南省医学科技攻关计划普通项目（201602085）
关键词
腮腺肿瘤
磁共振成像
扩散
Parotid neoplasms
Magnetic resonance imaging
Diffusion
