摘要
目的分析加巴喷丁与卡马西平治疗复发性三叉神经痛的临床效果。方法将2016年1月~2017年8月于本院进行治疗的60例复发性三叉神经痛患者作为研究对象,回顾性分析该60例患者的病历资料,按照治疗方式的不同将患者分成两组,普通组使用卡马西平进行治疗,实验组采用加巴喷丁进行治疗,对比分析两组患者的治疗效果。结果治疗后,实验组患者的VAS评分为(2.5±0.5)分,LSI-B指数为(16.5±2.1),各项指标均优于普通组(P<0.05);实验组患者的治疗有效率为93.33%,不良反应发生率为3.33%,两项数据均优于普通组(P<0.05)。结论加巴喷丁治疗复发性三叉神经痛的效果明显优于卡马西平,该药可有效缓解患者疼痛,且药物不良反应更少,用药安全可靠,能够显著提升患者的生活质量,应在复发性三叉神经痛的治疗中优先选用。
Objective To investigate the clinical effectiveness of gabapentin and carbamazepine on recurrent trigeminal neuralgia. Methods 60 patients with recurrent trigeminal neuralgia in our hospital from January 2016 to August 2017 were selected. Their medical records were analyzed retrospectively and divided into two groups according to treatments.Patients in general group were treated with carbamazepine while patients in study group were treated with gabapentin.Clinical effectiveness in two groups were compared and analyzed. Results Score of VAS was（2.5±0.5） and the index of LSI-B was（16.5±2.1） in study group. Every index was better than that in general group（P〈0.05）. The effective rate of treatment was 93.33% and the incidence of adverse reaction was 3.33% in study group, which were both better than those in general group（P〈0.05）. Conclusion The effectiveness of gabapentin on recurrent trigeminal neuralgia is better than carbamazepine. Gabapentin could relieve patients＇ pain with fewer adverse reaction and safety. It could improve the life quality of patients and thus, should have the priority on being applied in the treatment of recurrent trigeminal neuralgia.
作者
李欣成
LI Xincheng(Pain Clinic, Zaozhuang TCM Hospital in Shandong Province, Zaozhuang 277100, China)
出处
《中国现代医生》
2018年第11期115-117,共3页
China Modern Doctor
关键词
加巴喷丁
卡马西平
复发性三叉神经痛
焦虑
抑郁
Gabapentin
Carbamazepine
Recurrent trigeminal neuralgia
Anxiety
Depression
