摘要
CEUS是纯血池显像,利用血液中含气微泡造影剂在声场中的非线性效应和强烈的背向散射获得对比增强图像,可动态直观地显示肿瘤微血管,已广泛应用于乳腺癌的诊断和疗效评估。CEUS在检出早期乳腺癌和识别前哨淋巴结方面具有较高敏感度和特异度,在评估新辅助化疗疗效、预测乳腺癌分子分型和辅助乳腺癌靶向治疗领域具有广阔的应用前景。本文对乳腺癌CEUS特点及其与生物标志物的关系、CEUS评价新辅助化疗疗效及辅助前哨淋巴结活检术方面的进展进行综述。
CEUS is a pure blood pool imaging depending on the non-linear effect and strong backscatter of gas-filled microbubbles in blood to obtain contrast-enhanced images. With the advantages of displaying tumor microvascular dynamically and intuitively, CEUS has been widely used for diagnosis and evaluating prognosis of breast cancers. CEUS has high sensitivity and specificity in detecting early breast cancers and identifying sentinel lymph nodes, with wide application prospects in assessing the efficacy of neoadjuvant therapy, predicting molecular typing and targeted therapy of breast cancers. The features of CEUS in breast cancers and the relationships with biomarkers, progresses in assessing neoadjuvant therapy and assisting sentinel lymph node biopsy were reviewed in the article.
作者
王云月
阮骊韬
任予
商静
党莹
WANG Yunyue;RUAN Litao;REN Yu;SHANG Jing;DANG Ying(Department of Ultrasound Medicine;Department of Breast Surgery, the First Affiliated Hospital, Xi＇an Jiaotong University, Xi＇an 710061, China)
出处
《中国医学影像技术》
CSCD
北大核心
2018年第4期633-636,共4页
Chinese Journal of Medical Imaging Technology
基金
陕西省重点研发计划一般项目(2017SF-132)
关键词
乳腺肿瘤
超声检查
造影剂
分子分型
肿瘤辅助疗法
前哨淋巴结
Breast neoplasms
Ultrasonography
Contrast media
Molecular typing
Neoadjuvant therapy
Sentinellymph node
