摘要
目的研究中药辅助治疗痰湿型多囊卵巢综合征合并不孕症的临床疗效。方法将中医辨证为痰湿型多囊卵巢综合征合并不孕症的62例患者随机分成观察组和对照组,对照组给予克罗米芬、达英-35等常规治疗,观察组在对照组基础上加用燥湿化痰补肾活血方加减治疗,观察2组治疗前后雌激素指标(FSH、LH、T、E_2)变化,并评价临床妊娠率及总体有效率。结果观察组治疗前后雌激素LH、T、E_2和FSH差值明显大于对照组,组间对比差异有统计学意义(P<0.05)。观察组周期排卵率为81.3%,对照组为80.0%,2组比较差异无统计学意义。观察组妊娠率为62.5%,总体有效率为90.6%,分别高于对照组的33.3%、70.0%,比较差异均有统计学意义(P<0.05)。结论常规治疗辅助燥湿化痰补肾活血方治疗痰湿型多囊卵巢综合征合并不孕症,能明显改善患者雌激素水平,提高临床妊娠率,疗效确切,具有研究推广价值。
Objective To study the clinical effect and safety of Chinese herbal medicine prescription in the treatment of phlegm-damp polycystic ovary syndrome with infertility. Methods 62 patients with TCM syndrome differentiation of polycystic ovary syndrome with infertility were randomly divided into observation group and control group. The control group received clomiphene,daun-35 and other conventional treatment. The observation group used dampness eliminating,eliminating phlegm,invigorating kidney and promoting blood circulation prescription on the basis of the control group. The changes of estrogen index（FSH,LH,T,E_2） before and after treatment were observed,and the clinical pregnancy rate and overall effective rate were evaluated. Results The difference of estrogen LH,T,E_2 and FSH before and after treatment was significantly larger than that of the control group,and the difference between the two groups was statistically significant（P〈0. 05）. The ovulation rate in the observation group and the control group was 81. 3% and 80. 0% respectively. There was no significant difference between the two groups. The pregnancy rate and the overall effective rate of the observation group was 62. 5% and90. 6%,which was higher than that of the control group（33. 3% and 70. 0%,respectively）. The difference was statistically significant（P〈0. 05）. Conclusion Traditional Chinese medicine for treating phlegm-dampness type polycystic ovary syndrome complicated with infertility due to auxiliary heat-drying,phlegm-eliminating,kidney-promoting and blood-activating prescription can obviously improve the estrogen level of the patient,improve the clinical pregnancy rate and the curative effect,and has the research and popularization value.
作者
卢艳杰
LU Yanjie(Department of Pharmacy, Jiyuan Hospital of Traditional Chinese Medicine, Henan Province, Jiyuan 459000, Chin)
出处
《光明中医》
2018年第5期664-666,共3页
GUANGMING JOURNAL OF CHINESE MEDICINE
