摘要
目的研究高频超声、钼靶X线单一及联合诊断触诊阴性乳腺癌与病理结果的一致性。方法回顾性分析笔者医院90例触诊阴性,钼靶X线检查发现微小钙化灶患者的临床病例资料,所有患者均进一步行高频超声检查,以病理穿刺活检为金标准,比较两种单一检查方法及联合诊断在触诊阴性乳腺肿瘤患者诊断中的应用价值。结果病理结果显示,良性肿瘤病灶58例,恶性肿瘤32例,其中0期10例,Ⅰ期18例,Ⅱ期4例。高频超声与病理结果一致性尚可(Kappa=0.641),其诊断乳腺癌AUC为0.775。钼靶X线与病理结果一致性良好(Kappa=0.725),AUC为0.830。高频超声联合钼靶X线诊断与病理结果高度一致(Kappa=0.879),AUC为0.934。联合诊断准确性显著高于高频超声(P<0.05)和钼靶X线(P>0.05)。结论高频超声和钼靶X线在触诊阴性乳腺癌诊断中各具优势,联合诊断有助于实现优势互补,与病理结果一致性高,有助于提高诊断准确性。
Objective To study the consistency between pathology and the single and combined diagnosis of negative breast cancer by ultrasonography and mammography. Methods 90 clinical case data of patients with palpable negative breast tumors and mammography revealed small calcifications were retrospective analyzed.All patients were received the high frequency ultrasound.The value of two methods and combined diagnosis in the diagnosis of breast cancer with palpation negative were compared,which the pathological biopsy was the gold standard. Results The pathological showed that there were 58 cases of benign tumors, 32 cases of malignant tumors,10 cases of stage 0, 18 cases of stage Ⅰ, 4 cases of stage Ⅱ.The high frequency ultrasonography was consistent with pathological（Kappa=0.641）.The AUC of diagnosiing the breast cancer was 0.775.The molybdenum target radiography was consistent with pathological（Kappa=0.725）, and the AUC was 0.830.The high frequency ultrasonography combined with molybdenum target radiography was highly consistent with pathological（Kappa=0.879）,and the AUC was 0.934.The accuracy of combined diagnosis was higher than that of high frequency ultrasound （P〈0.05） and molybdenum target radiography（P〉0.05）. Conclusion The high frequency ultrasonography and molybdenum target radiography have advantages in the diagnosis of palpable negative breast cancer.The joint diagnosis helps to achieve complementary strengths,has high consistency with pathology,and help to improve the diagnostic accuracy.
作者
秦福才
李银珍
叶明
Qin Fucai, Li Yinzhen, Ye Ming.(Department of Ultrasound Imaging, Hubei Hospital of Integrated Traditional Chines)
出处
《医学研究杂志》
2018年第3期74-78,共5页
Journal of Medical Research
基金
湖北省自然科学基金资助项目(2014CFB146)
关键词
高频超声
钼靶X线
触诊阴性
乳腺癌
High frequency ultrasound
Molybdenum target radiography
Palpation negative
Breast cancer
