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中西医结合治疗慢性盆腔炎疗效观察及安全性分析 被引量:65

Clinical Efficacy and Safety Analysis of Traditional Chinese Combined with Western Medicine in Treatment of Chronic Pelvic Inflammatory Disease
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摘要 目的:分析中西医结合治疗慢性盆腔炎临床疗效观察及安全性,以供不断提高慢性盆腔炎临床疗效参考。方法:选取医院2015年3月—2017年3月收治的117例慢性盆腔炎患者为研究对象,按随机数字表法分为观察组和对照组。对照组58例患者仅给予西医治疗,观察组59例患者给予中西医结合治疗。对比两组治疗前后相关生化指标变化情况、治疗后阳性体征情况以及安全性。结果:治疗后,观察组C-反应蛋白(4.08±0.70)mg/L、全血黏度低切(9.68±1.16)m Pa/s、全血黏度高切(5.17±0.47)m Pa/s以及盆腔积液(5.08%)、附件压痛(6.78%)、阳性体征总发生率(16.95%)与对照组C-反应蛋白(6.90±1.40)mg/L、全血黏度低切(12.03±1.50)m Pa/s、全血黏度高切(6.30±0.40)m Pa/s以及盆腔积液(17.24%)、附件压痛(27.59%)、阳性体征总发生率(68.29%)相比明显降低,其白细胞介素-2(5.06±0.51)ng/m L、白细胞介素-10(24.20±2.90)ng/m L和对照组白细胞介素-2(4.10±0.40)ng/m L、白细胞介素-10(19.90±2.51)ng/m L比较明显升高;差异具有统计学意义(P〈0.05)。结论:对于慢性盆腔炎患者来说,应用中西医结合治疗,可显著改善患者相关体征及其生化指标水平,同时药物不良反应较低,安全性高。 Objective: To analyze the clinical efficacy and safety of traditional Chinese medicine combined with Western medicine in the treatment of chronic pelvic inflammatory disease in order to improve the clinical efficacy of chronic pelvic inflammatory disease. Methods: Totally 117 cases of chronic pelvic inflammatory disease patients in our hospital from March 2015 to March 2017 were selected as the research object,and randomly divided into the observation group and the control group according to random number table method. A total of 58 cases of patients of the control group were treated with Western medicine only and 59 cases of patients of the observation group were treated with traditional Chinese combined with Western medicine. Before and after treatment the relevant biochemical indicators,positive signs and safety were compared. Results: After treatment,the observation group's C-reactive protein( 4. 08 ± 0. 70) mg/L,low shear whole blood viscosity( 9. 68 ± 1. 16) m Pa/s,whole blood viscosity at high shear rate( 5. 17 ± 0. 47) m Pa/s and pelvic effusion( 5. 08%),adnexal tenderness( 6. 78%) and the total incidence of positive signs( 16. 95%) were lower than the control group's C-reaction protein( 6. 90 ± 1. 40) mg/L,low shear whole blood viscosity( 12. 03 ± 1. 50) m Pa/s,whole blood viscosity at high shear rate( 6. 30 ± 0. 40) m Pa/s and pelvic effusion( 17. 24%),adnexal tenderness( 27. 59%)and the total incidence of positive signs( 68. 29%). The interleukin-2( 5. 06 ± 0. 51) ng/m L and interleukin-10( 24. 20 ± 2. 90) ng/m L were significantly increased than the control group's interleukin-2( 4. 10 ± 0. 40) ng/m L and interleukin-10( 19. 90 ± 2. 51) ng/m L,and the difference was statistically significant( P〈 0. 05). The total incidence of adverse reactions in the observation group( 3. 39%) were compared with 10. 34% of the control group,and the difference was not statistically significant( P〈 0. 05). Conclusion�
作者 贾利平 刘玉珠 周小飞 JIA Liping;LIU Yuzhu;ZHOU Xiaofei(Department of Gynaecology, The Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan, China)
出处 《中华中医药学刊》 CAS 北大核心 2018年第4期939-941,共3页 Chinese Archives of Traditional Chinese Medicine
基金 海南省自然科学基金项目(20168294)
关键词 慢性盆腔炎 中西医结合治疗 临床疗效 chronic pelvic inflammatory disease traditional Chinese combined with Western medicine clinical efficacy
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